抑郁症相关性失眠虚实证候睡眠模式的比较研究

Comparisons of Sleep Patterns Between Patients of Deficiency Syndrome and Excess Syndrome in Depressive Insomnia

目的初步探讨抑郁症相关性失眠患者虚实证候间睡眠模式是否存在差异。方法对63例符合标准的抑郁症相关性失眠患者,进行汉密尔顿抑郁17项量表(HAMD-17)、匹兹堡睡眠质量指数(PSQI)检查,通过中医辨证分为虚证组与实证组,运用多导睡眠图(PSG)监测技术分析两组患者的睡眠结构及睡眠进程,对所收集的资料采用卡方、t检验等方法进行统计,评价两组间睡眠模式的关系。结果虚证患者慢波睡眠较实证患者时间及所占比例有所减少(P<0.05),而两者间睡眠进程无明显差异。结论抑郁症相关失眠患者存在睡眠结构的改变,慢波睡眠时间减少,尤以虚证患者更为突出。

Abstracts：Objective To investigate the mode between deficiency syndrome and excess syndrome in patients with depressive insomnia if there are different.M ethods 63 patients with depressive insomnia were divided into deficiency syndrome group and excess syndrome group.All patients with Depression Scale 17 （HAMD -17）, Pittsburgh Sleep Quality Index （PSQI） examination, clinical symptoms were observed.Using Polysomnogram to analysis the sleep architecture and the sleep process.The correlation was analyzed by t -test and chi -square test.Results Deficiency of insomnia patients with slow wave sleep time and proportion decreased compared with excess insomnia pa-tients （P 〈0.05）, but no significant difference between two groups in sleep process excess.Conclusion Patients with depressive insomnia have sleep structure changes, slow wave sleep time reduced, especially in patient with deficiency syndrome is more outstanding .