液基细胞学检测在宫颈疾病诊断中的应用

Application of Liquid-based Cytology Test in the Diagnosis of Cervical Disease

目的:探讨液基细胞学检测在宫颈疾病诊断中的应用价值。方法:采用子宫颈细胞学Bethesda报告系统(TBS)对笔者所在医院2012年11月-2013年5月妇产科门诊及住院收集的宫颈刷检液基标本进行描述性诊断及建议。结果:有组织病理对照的68例中可发现:鳞状细胞癌(SCC)2例(2.94%),宫颈鳞状上皮内瘤变CINⅢ级10例(14.71%),宫颈鳞状上皮内瘤变CINⅡ级16例(23.53%),宫颈鳞状上皮内瘤变CINⅠ级或人乳头瘤病毒感染共24例(35.29%),慢性宫颈炎16例(23.53%)。微生物感染提示:阴道菌群失调591例(9.85%),霉菌感染160例(2.67%),滴虫感染78例(1.30%),放线菌属感染4例(0.07%),其中滴虫合并霉菌感染2例、滴虫合并放线菌属感染1例。结论:液基细胞学检测在宫颈癌、宫颈癌前病变筛查及宫颈微生物感染疾病诊断中具有意义。

Objective： To investigate the value of liquid-based cytology test in the diagnosis of cervical disease.Method： Liquid-based samples were collected employing cervix brushes from November 2012 to May 2013 in the outpatient and inpatient department of gynecology and obstetrics of our hospital which were given a descriptive diagnosis and advice using the cervical cytology bethesda system（TBS）.Result： In 68 cases which compared with histopathology, we found 2 cases of squamous cell carcinoma（SCC）（2.94%）, 10 cases of cervical intraepithelial neoplasia CINI（14.71%）, 16 cases of cervical intraepithelial neoplasia CINli（23.53%）, 24 cases of cervical intraepithdial neoplasia CINI or human papilloma virus（HPV） infection（35.29%）, 16 cases of chronic cervicitis（23.53%）.Cervix organism infection prompted： 591 cases（9.85%） with vaginal dysbacteriosis, 160 cases（2.67%） with fungus infection, 78 cases（1.30%） with trichomonad infection, 4 cases（0.07%） with actinomyces infection, contained 2 cases with trichomonad and fungus co- infection, 1 case with trichomonad and actinomyces co-infection.Conclusion： Liquid-based cytology test is significant in screening of cervical carcinoma,cervical intraepithelial neoplasia and diagnosis of cervical microbial infection disease.