四逆四君子汤加味治疗肝郁脾虚型慢性胃炎的临床效果

Clinical effect of modified Sini Sijunzi decoction treating chronic gastritis of type liver depression and spleen deficiency

目的：探讨四逆四君子汤加味治疗肝郁脾虚型慢性胃炎的临床效果。方法选取本院2012年1月-2014年1月收治的肝郁脾虚型慢性胃炎患者60例，将其随机分为实验组和对照组，实验组给予四逆四君子汤加味治疗，对照组给予常规西医治疗。治疗4周后，比较两组的疗效。结果实验组的总有效率为93.3%，明显高于对照组的（76.7%）（P〈0.05）；两组治疗后的中医证候积分均明显下降（P〈0.05），且实验组治疗后的中医证候积分明显低于对照组（P〈0.05）；两组的不良反应发生率差异无统计学意义（P〉0.05）。结论四逆四君子汤加味治疗肝郁脾虚型慢性胃炎可明显提高效果，且其毒副作用小，安全性高，值得临床推广。

Objective To investigate the clinical effect of modified Sini Sijunzi decoction treating chronic gastritis of type liver depression and spleen deficiency. Methods 60 patients with chronic gastritis of type liver and spleen defi-ciency treated in our hospital from January 2012 to January 2014 were randomly divided into experimental group and control group,the experimental group was treated with modified Sini Sijunzi decoction,while control group was treated with conventional western medicine.After 4 weeks treatment,the curative between two groups was compared. Results The total effective rate in experimental group （93.3%） was significantly higher than that of control group （76.7%） （P〈0.05）;TCM syndrome integral of two groups after treatment was obviously decreased,and TCM syndrome integral of ex-perimental group was obviously lower than that of control group （P〈0.05）;there was no statistical difference of the inci-dence rate between two groups （P〉0.05）. Conclusion Modified Sini Sijunzi decoction treating chronic gastritis of type liver depression and spleen deficiency can improve obviously the curative effect with small side effect and high aafety.It is worthy of clinical promotion.