摘要
牛磺酸是人体内一种极为重要的氨基酸,也是中枢神经系统（CNS）中水平最为丰富的游离氨基酸.牛磺酸作为人体的一种条件必需氨基酸,具有广泛的生理药理作用.尤其在CNS的发育中,牛磺酸作为一种神经递质,能保持膜的结构完整性,调节钙的转运和稳态,还可作为营养因子、渗透剂、神经调节剂、神经保护剂发挥着重要作用.现就牛磺酸的理化性质、来源与分布、合成与代谢、吸收与转运,及其对CNS的保护作用做一综述.
Taurine is one of the extremely important amino acids in the body,and is also the most abundant free amino acids in the central nervous system（CNS）.Taurine as a conditional essential amino acids exerts a wide range of physiological and pharmacological effects.Taurine,especially as a neurotransmitter in the developing CNS,can maintain the structural integrity of the membrane,regulate calcium transport and calcium homeostasis,also as nutritional factors,osmolyte,neuromodulator,neuroprotective agents,plays an important role.In this paper,physiological and biochemical properties of taurine,source and distribution in vivo,synthesis and metabolism,absorption and transport,and its protective effect on the CNS are reviewed.
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2015年第8期635-637,共3页
Chinese Journal of Applied Clinical Pediatrics
基金
国家自然科学基金（81170577）
关键词
牛磺酸
理化性质
来源与分布
合成与代谢
吸收与转运
中枢神经系统
神经保护
Taurine
Physiological and biochemical properties
Source and distribution
Synthesis and metabolism
Absorption and transport
Central nervous system
Neuroprotection
