胰岛素泵联合诺和灵30R治疗糖尿病合并肺部感染的疗效及检验指标分析

The clinical efficiency of insulin pump therapy combined with Novolin 30R in patients with diabetes mellitus complicated with pulmonary infection and analysis of detection indexes

目的分析精蛋白生物合成人胰岛素注射液(预混30R)(又称诺和灵30R)联合胰岛素泵治疗糖尿病合并肺部感染的疗效及检验指标。方法选取2010年1月至2013年2月糖尿病合并肺部感染患者90例,分为对照组与观察组,各45例。对照组给予诺和灵30R治疗和常规治疗,观察组在对照组基础上加用胰岛素泵治疗,比较两组治疗后的临床效果及检验指标。结果对照组的治愈率为51.11%,总有效率为82.22%;观察组的治愈率为84.44%,总有效率为100.00%,两组治愈率及总有效率比较差异均有统计学意义(P<0.05)。两组患者住院时间、血糖达标时间、胰岛素使用剂量、体温恢复时间、住院费用、并发症发生率,以及血钠、血钾、血酮、尿素氮水平和渗透压、PH值比较差异均有统计学意义(P<0.05)。结论诺和灵30R联合胰岛素泵治疗糖尿病合并肺部感染临床效果满意。

Objective To investigate the clinical efficiency of Isophane Protamine Biosynthetic Human Insulin Injection （pre‐mixed 30R）（Novolin 30R） combined with insulin pump therapy in patients with diabetes mellitus complicated with pulmonary in‐fection ,and to analyze the detection indexes .Methods From Jan .2010 to Feb .2013 ,90 cases of patients with diabetes mellitus complicated with pulmonary infection were selected and divided into the observation group and control group .The control group received Novolin 30R treatment and conventional treatment ,the observation group were given insulin pump therapy based on the treatment of control group .The clinical efficiency and detection indexes were compared and analyzed .Results The cure rate and total effective rate were 51 .11% and 82 .22% respectively in the control group ,and were 84 .44% and 100 .00% in the observation group respectively .There were significant differences of both cure rate and total effective rate between the two groups （P〈0 .05） . There were statistically significant differences of hospitalization time ,the time for reaching target of glucose ,insulin dose ,recovery time of body temperature ,hospital costs ,incidence rate of complications ,serum levels of sodium ,potassium and urea nitrogen ,osmolality and PH value between the two groups（P〈0 .05） .Conclusion The combination of Novolin 30R and insulin pump therapy could provide satisfactory clinical efficiency in patients with diabetes mellitus complicated with pulmonary infection .