新生儿窒息多器官功能损害的临床研究

Clinical Study on Multiple Organ Injury in Neonates With Asphyxia

目的：对新生儿窒息后多器官功能损害的临床特点进行分析。方法选取我院2010年4月-2014年4月收治的120例窒息新生儿，分析其临床资料。结果共有96例窒息新生儿出现了器官功能损害，占窒息新生儿总数的80%。其中多器官损害的发生率为53.3％，胃肠损害发生率为16.6%，肝损害发生率为31.6%，肾损害发生率为35%，肺损害发生率为41.6%，心脏损害发生率为46.6%，脑损害发生率为69.1%。其中重度窒息患儿的多器官功能损害发生率为69.4%，病死率为19.4%，轻度窒息患儿多器官功能损害发生率为33.3%，病死率为18.75%，两者的差异具有统计学意义（P〈0.05）。结论要加强围产期的保健，提高心肺复苏和复苏后的监护，降低新生儿窒息的发生率。

Objective To analyze the clinical characteristics of multiple organ function damage in neonatal asphyxia. Methods 120 patients of neonatal asphyxia were selected in our hospital from April 2010 to April 2014,analysed the clinical data. Results A total of 96 cases of neonatal asphyxia had organ damage,accounting for 80% of the total number of neonatal asphyxia. The incidence of multiple organ damage was 53.3%,the incidence of gastrointestinal injury incidence was 16.6%,the incidence of liver damage was 31.6%,the incidence of renal damage was 35%,lung injury incidence was 41.6%,heart injury incidence was 46.6%,the incidence of brain damage was 69.1%. The multiple organ function damage in children with severe asphyxia rate was 69.4%,the fatality rate was 19.4%,and mild asphyxia multiple organ dysfunction rate was 33.3%, the fatality rate was 18.75%. The difference had statistically significant（P〈0.05）. Conclusion We should be strengthen perinatal health care, improve the new resuscitation and resuscitation of neonatal asphyxia,reduce the rate of decrease.