苯丙胺类兴奋剂所致精神障碍临床特征分析

The Clinical Features of Mental Disorder Due to Amphetamine Type Stimulants

目的：探讨苯丙胺类兴奋剂所致精神障碍临床特点。方法对2010-2013年在南宁市社会福利医院药物依赖科住院治疗的132例ATS所致精神病性障碍临床资料进行回顾性分析。结果滥用ATS类兴奋剂男女性别差异不大，文化素质偏低职业以无业和个体为主。76例（57.6％）曾经使用或合并使用其他物质。常见的精神病性症状为幻听112例（84.8％）、被害妄想124例（93.9％）、嫉妒妄想96例（72.7％）、易激惹120例（90.9％）、兴奋状态124例（93.9％）、冲动行为104例（78.8％）。经治疗症状在一个月内显效率97.4％。结论长期滥用苯丙胺类兴奋剂可致严重的精神病性障碍。治疗以对症治疗为主，并辅以心理治疗，总体疗效尚佳。

Objective To discuss the clinical features of mental disorder due to amphetamine type stimulants. Methods 132 Clinical data of psychotic disorder caused by ATS were retrospectively was analyzed from 2010 to 2013 in Nanning City Social Welfare Institute in Drug Dependence department. Results The abuse of amphetamine type stimulants had no sex difference. The low cultural quality was to unemployed and individual. 19 cases（57.6%）had used or combined with other substances. Psychotic symptoms common to auditory hal ucinations in 28 cases（84.8%）,31（93.9%）cases of paranoia, delusions of jealousy in 24 cases（72.7%）,irritable in 30 cases（90.9%）,the excited state in 31 cases（93.9%）,impulsive behavior in 26 cases（78.8%）. After treatment,the significantly efficiency of symptoms was 97.4% within a month. Conclusion The mental disorders can be severe if abuse amphetamine type stimulants. Symptomatic treatment,supplemented by psychological treatment,the overal effect is comparatively good.