应用艾司西酞普兰治疗强迫症的临床效果探析

Clinical Effect Analysis of Escitalopram in Treatment of Obsessive-compulsive Disorder

目的：探析艾司酞普兰对强迫症的临床治疗效果。方法选取我院2012年-2014年收治的52例强迫症患者为研究对象，随机分成实验组26例使用艾司西酞普兰治疗，对照组26例使用多虑平治疗，采用Yale-Brown强迫量表、汉斯顿焦虑量表、副反应量表来评价两组的临床疗效，统计处理相关数据。结果经药物治疗，实验组患者痊愈6例，显效10例，总有效率88.5%；对照组患者痊愈2例，显效7例，总有效率为69.2%，对比差异有统计学意义（P〈0.05）；实验组患者副反应少于对照组（P〈0.05）。结论艾司西酞普兰治疗强迫症效果良好，且副反应相对较少。

Objective To analyze clinical effect of escitalopram in treatment of obsessive-compulsive disorder. Methods 52 patients with obsessive-compulsive disorder in our hospital from 2012 to 2014 were randomly selected into experimental group（26 cases）and control group（26 cases）. The patients in experimental group were treated with escitalopram ,the control group patients were treated with doxepin .The clinical effects of two groups were evaluated using Yale-Brown Obsessive Compulsive Scale,Hanston anxiety scale and treatment emergent symptom scale,the statistical data were processed. Results In the experimental group,there were 6 cured cases,10 effective cases,the total efficiency was 88.5%.In the control group, there were 2 cured cases,7effective cases,the total effective rate was 69.2%,and the difference was significant（P〈0.05）. The side reactions in experimental group were significantly less than the control group（P〈0.05）. Conclusion The clinical effect of escitalopram in treatment of obsessive-compulsive disorder is good,and the side reaction is relatively less.