喉结核患者生活方式影响其发病的多因素分析

Multiplicity of life ways of patients with laryngeal tuberculosis influencing its onset

目的 通过调查探索喉结核病人的生活方式在其发病中的影响关系.方法 选择2013年1月至2014年12月2年间于广州市胸科医院就医的喉结核病患者和健康体检者各50例,制定调查表进行统一调查,对17个变量进行单因素条件Logistic回归分析,筛选出有统计学意义的变量再采用多因素条件Logistic回归分析.结果 单因素分析发现9个变量与喉结核的发病有关,分别是：性别、居住地、文化程度、职业、收入、睡眠时间、饮食习惯、吸烟、接触TB史;经多因素分析最终筛选出6个与喉结核发病有关的影响因素,分别是：性别、居住地、文化程度、职业、工作压力、接触TB史（P＜0.05）.结论 男性、居住在城市、文化程度低、低收入、睡眠不足、吸烟等不良生活习惯及肺结核传染风险等均是影响喉结核发病的危险因素.

Objective To explore the life ways of patients with laryngeal tuberculosis influencing its onset through investigation.Methods 50 patients with laryngeal tuberculosis and 50 healthy check-up persons were recruited from Guangzhou Chest Hospital from January,2013 to December,2014.Interview was carried out with a unified investigation questionnaire.Variables of statistical significance screened from 17 variables by univariate conditional Logistic regression analysis were further subjected to multivariate conditional Logistic regression analysis.Results The univariate analysis found that 9 variables associated with the pathogenesis of laryngeal tuberculosis,including gender,place of residence,education level,occupation,income,sleep,diet,smoking,and contact history of TB.The 9 variables above were introduced into the model by multivariate analysis,and 6 variables of statistical significance screened,including gender;place of residence,education level,occupation,work pressure,contact history of TB（P〈0.05）.Conclusions Male,living in urban district,low education level,low income,inadequate sleep,smoking,etc.and risk of lung tuberculosis infection are the risk factors affecting laryngeal tuberculosis.