摘要
目的：探讨纳米碳混悬液在甲状腺手术中对甲状旁腺的保护和应用。方法80例甲状腺肿瘤患者采用随机数字表法随机分为对照组和观察组，观察组术中行腺体内纳米碳注射后行切除术，对照组仅行手术切除，比较2组术后血钙、甲状旁腺素（ parathyroid hormone ，PTH）的改变情况。结果观察组低血钙发生5例，对照组发生15例，差异有统计学意义（χ2＝6.6667，P＜0.05）；观察组PTH下降5例，对照组发生14例，差异有统计学意义（χ2＝5.5910，P＜0.05）；病理结果证实误切甲状旁腺观察组0例，对照组6例、11枚，差异有统计学意义（χ2＝4.5045，P＜0.05）。结论纳米碳在甲状腺手术中的应用，有助于甲状腺旁腺的鉴别保护，降低甲状旁腺的损伤。
Objective To discuss the protection of parathyroid ancl application of nano-carhon suspen- sion in thyroid surgery. Methods 80 cases were randomly divided into 2 groups： the experimental group which were injected nano-carbon into thyroid during thyroidectomy, and the control group without any injection. Results There were 5 cases with hypocalcemia and 5 cases with PTH decrease in the experimental group, and there were 15 cases and 14 cases respectively in the control group. Pathological results showed that misresection of par- athyroids occurred in 6 cases of the control group（ 11 parathyroid glands）were while it didn＇t happen in the experi- mental group. Conclusion Nano-carbon can help to identify and protect the parathyroid, decreasing the proba- bility of parathyroid gland damage during thyroid surgery.
出处
《中华内分泌外科杂志》
CAS
2015年第2期144-146,共3页
Chinese Journal of Endocrine Surgery
基金
国家自然科学基金（81372863）
郑州市科技领军人才项目（131PLJRC676）
