矿区居民胃食管反流病相关危险因素分析

RELATIVE RISK FACTORS OF GASTROESOPHAGEAL REFLUX DISEASE AMONG MINING AREA RESIDENTS

目的分析矿区居民胃食管反流病(GERD)的相关危险因素,为矿区居民提供科学的防治措施。方法使用胃食管反流病量表(RDQ)调查胃食管反流症状的患者,RDQ评分≥12分或者胃镜下有反流性食管炎典型图像作为病例组,以非GERD患者作为对照组,分析可能的危险因素,有统计学意义的因素进一步作Logistic回归。结果单因素分析显示年龄、腹围、体重指数(BMI)、性别、咖啡、油腻食物、进食过饱、食管裂孔疝(HH)、辛辣食物、幽门螺旋杆菌(Hp)、劳累、非甾体抗炎药(NSAIDs)、便秘、职业与矿区居民GERD相关(P<0.05);多因素Logistic回归显示Hp(OR=3.005,P=0.020)、劳累(OR=0.150,P=0.001)、辛辣食物(OR=9.166,P=0.000)、便秘(OR=13.969,P=0.000)为矿区居民GERD的危险因素。结论提高对GERD相关危险因素的认识,通过对矿区居民加强健康教育、倡导科学的饮食、养成良好的生活习惯和个体化的治疗,提高矿区居民的生活质量。

Objective To analyze related risk factors for GERD residents of the mining area,and to provide a scientific control measures.Methods The patients with gastroesophageal reflux symptoms were investi-gated by using gastroesophageal reflux disease （RDQ）scale,RDQ score≥12 points or endoscopically with reflux esophagitis image were as a typical case group,non- GERD patients as the control group.Some possible risk factors were analyzed in two groups.Results Univariate analysis showed that age,waist circumference,body mass index （BMI）,sex,coffee hobby,greasy food,eating too full,hiatal hernia （HH）,spicy foods,Helicobacter pylori （Hp）infection,fatigue,non-steroidal anti-inflammatory drugs （NSAIDS）,constipation,GERD-related career were relative with GERD mine residents （P 〈005）.Mul-tivariate Logistic regression analysis showed that Hp （OR=3.005,P =0.020）,fatigue （OR=0.150,P =0.001）,spicy foods （OR=9.166,P = 0.000）,constipation （OR=13.969,P =0.000）were the risk fac-tors for GERD mine residents.Conclusion Raising awareness of risk factors associated with GERD for mining area residents can improve the quality of life by enhancing health education,advocating science diet, developing good habits and individualized treatment.