褪黑素生理活性及其作用机制的研究进展

Progress on physiological activities of melatonin and its mechanisms

松果体是人体重要的神经内分泌腺,褪黑素是松果体分泌的一种吲哚类神经内分泌激素,具有十分广泛的生理作用。研究发现,褪黑素在催眠、重建和稳定生物节律、免疫调节、生殖系统、神经系统、消化系统,以及抗氧化、抗衰老、抗肿瘤等方面都具有一定的生物学效应。本文综述了有关褪黑素研究的国内外最新进展,对其主要的生物学作用及机制进行了探讨。

The pineal gland is a neuroendocrine gland.Melatonin is a kind of neuroendocrine hormone secreted by the pineal gland, which has a wide range of physiological effects.Many researches found that melatonin have certain biological effects in hypnosis, reconstruction and stabilization of biological rhythm, immune regulation, reproductive system, nervous system, digestive system, and antioxidant, anti-aging, anti -tumor etc..This paper reviewed the latest progress of the domestic and foreign research related to melatonin, and discussed its biological effects and mechanisms.