清血通脉颗粒喷雾制粒工艺的正交试验法优化

Orthogonal test optimization Qingxue Tongmai particle spray granulating process

目的优化清血通脉颗粒的最佳喷雾制粒工艺条件。方法采用正交试验法,以颗粒成品率和丹参酮ⅡA转移率为考察指标,对影响清血通脉颗粒喷雾制粒过程的主要因素进行考察。结果最佳工艺参数为：雾化压力0.25MPa,进口温度为95-100℃,出口温度为60-70℃,流浸膏相对密度为1.10（80℃）。结论该工艺条件合理,制出的颗粒质量稳定,为工业化生产提供了实验依据。

Objective To optimize Qingxue Tongmai panicle best spray granulating process conditions. Methods Using the orthogonal test method, with grain yield and tanshinone Ⅱ A transfer rate as the inspection indexes, the influence Qiugxue Tongmai particle spray granulating process of the main factors on investigation. Results The best technological parameters： atomization pressure 0.25Mpa, inlet temperature 95 - 100℃, outlet temperature 60 - 70℃, extract relative density 1.10 （ 80℃ ）. Conclusion The process conditions are reasonable, which panicles stable quality, provide and experimental basis for industrial production.