壳聚糖接枝聚乙烯吡咯烷酮复合碘膜的制备及其性能

Preparation and Performance of Chitosan Grafted Polyvinyl Pyrrolidone Film with Iodine

壳聚糖（CTS）在N2气保护下以偶氮二异丁酸二甲酯（AIBME）为引发剂接枝聚乙烯吡咯烷酮（PVP）,加碘乙醇溶液并与明胶溶液共混制备CTS-PVP复合碘膜。通过红外（IR）、扫描电子显微镜（SEM）、紫外-可见（UV-Vis）、差示扫描量热法（DSC）等技术手段对其表征。UV结果表明,CTS/PVP复合碘膜在200~600 nm之间具有强吸收。其玻璃化转变温度为319℃,具有很好的热稳定性。抑菌性测试表明其抑菌度随着加碘量的增加而增大,当CTS-PVP-I2复合液体积≥10 m L时,其对金黄色葡萄球菌和大肠杆菌的抑菌环直径均在16~36mm之间,为高度敏感,具有良好的杀菌效果。

The CTS-PVP film with iodine was prepared by chitosan （CTS） grafted polyvinyl pyrrolidone （PVP） in the protection of N2 with dimethyl 2,2＇-azobis （2-methylpropionate） （ AIBME ） as initiator followed by addition of a certain amounts of iodine in ethanol solution and a gelatin solution. The properties of the film were characterized by infrared （IR） , scan electron microscopy （ SEM ） , UV-visible spectroscopy （ UV-Vis）, differential scanning calorimetry（ DSC）, etc. The UV-Vis spectrum shows a strong absorption between 200 ~ 600 nm for the CTS-PVP film with iodine. The glass transition temperature at 319 ℃ indicates a good thermal stability. The antimicrobial test result shows that the inhibition zone diameters increase along with the increasing amounts of CTS-PVP-I2 complex liquid. The inhibition zone diameters against Staphylococcus aureus and Escherichia coli are in the range of 16 ~ 36 mm, when the added volume of CTS-PVP-I2 complex fluid is 10 mL or more, implying its high sensitivity and good antibacterial properties.