降钙素原联合呼吸道病原体抗体检测在小儿肺炎的诊断价值

Diagnosis Value of PCT Combined with Respiratory Pathogen Detection in Pneumonia in Children

目的探讨血清降钙素原（PCT）联合呼吸道病原体抗体检测在小儿肺炎中的诊断价值。方法收集2013年7月～2014年1月收治住院的肺炎患儿1256例，采用化学发光法检测PCT，采用酶联免疫法检测肺炎支原体，肺炎衣原体及呼吸道常见病毒。结果PCT阳性率为30．7％，肺炎支原体IgM、肺炎衣原体IgM、呼吸道舍胞病毒IgM、腺病毒IgM及流感病毒AIgM阳性率分别为21_4％，16．8％，11．8％，8．4％和10．9％；PCT在不同性别的患儿中阳性例数最多，分别为男性227例和女性158例，但PCT和呼吸道病原体抗体阳性在不同性别中差异无统计学意义（P〉0．05）；在不同年龄组中，PCT阳性例数在≤1岁组中最多，肺炎支原体IgM和肺炎衣原体IgM阳性例数则在1～3岁组中例数最多，不同的呼吸道病毒阳性例数最多表现在不同的年龄组。PCT和呼吸道病原体抗体阳性在不同年龄中差异无统计学意义（P〉0．05）。结论PCT联合呼吸道病原体抗体检测有助于临床确定小儿肺炎类型，为小儿肺炎的诊治提供帮助。

Objective To investigate the diagnosis value of serum procalcitonin（PCT） detection combined with antibody detection of respiratory pathogens in children with pneumonia. Methods 1 256 cases of pneumonia in children were collected in the hospital from 2013 July to 2014 January were analyzed,detection PCT by chemiluminescence, using enzyme linked immunosorbent assay for detection of Mycoplasma pneumoniae ,Chlamydia pneumoniae and common respiratory virus. Results The positive rates of PCT was 30.7% ,and MP IgM,CP IgM,RSV IgM,ADV IgM and FLUA IgM were 21.4% ,16. 8%, 11.8% ,8.4% ,and 10.9%. PCT in children with different gender in the largest number of positive cases,respectively,male 227 cases and female 158 cases,but the PCT and respiratory pathogen antibody positive in different gender did not exist statistical difference （P〉0.05）. In different age groups,procalcitonin positive cases in 1 years in the group most,Mycoplasma pneumoniae and Chlamydia pneumoniae IgM positive cases in 1- 3 years old were the largest number, the number of respiratory virus positive patients with different maximum performance in different age groups. PCT and respiratory pathogen antibody positive in different age there was no statistical difference （P〉0.05）. Conclusion The PCT combined with respiratory pathogen detection of antibodies help the clinic to determine the type of pneumonia in children, to provide help for the diagnosis and treatment of pneumonia in children.