120例慢性咳嗽患者的病因分析及疗效观察

The Cause Analysis and Curative Effect Observation of 120 Chronic Cough Patients

目的:探讨东莞常平地区慢性咳嗽的病因构成及治疗效果。方法:采用中华医学会和美国胸科医师学会制定的慢性咳嗽诊治指南,对120例慢性咳嗽患者的病因进行分析,根据临床表现、辅助检查和经验性治疗效果综合判断;针对慢性咳嗽的病因给予特异性治疗,停药4周后判断疗效。结果:120例慢性咳嗽患者中明确诊断112例(93.3%),其中单一病因104例,前5位病因分别为咳嗽变异性哮喘(CVA)、上气道咳嗽综合征(UACS)、胃食管反流性咳嗽(GERC)、感染后咳嗽(PIC)、变应性咳嗽(AC);112例病因诊断明确者经特异性治疗后治愈30例(25.0%),有效75例(62.5%),无效7例(5.8%)。结论:CVA、UACS和GERC是东莞常平地区慢性咳嗽的常见原因,多数患者经针对病因的治疗后症状能够缓解。

Objective ： To explore the etiology structure and therapeutic effect of chronic cough in Dongguan Changping area.Method： Totally 120 patients with chronic cough were diagnosed using a diagnostic protocol based on the guideline on diagnosis and treatment of chronic cough established by Chinese medical association and the american college of chest physicians, which included clinical manifestation, auxiliary examination and empirical treatment effect.The curative effect was judged after specific treatment and drug withdrawal 4 weeks.Result： The cause of chronic cough was confirmed in 112 patients （ 93.3% ）, with a single cause found in 104 patients.The top 5 important single cause of cough were ： cough variant asthma （ CVA ）, upper airway cough syndrome （ UACS ）, gastroesophageal reflux （ GERC ）, post- infection cough （ PIC ）, atopic cough （ AC ） .After specific therapy based on diagnosis, cough disappeared in 30 patients （ 25.0% ）, alleviated in 75 patients （ 62.5% ） and had no changed in 7 patients （ 5.8% ） .Conclusion： CVA, UACS and GERC are the most common causes of chronic cough in Dongguan changping area.Specific therapy based on definite cause can result in a good outcome.