32例窒息新生儿大脑中动脉频谱的监测及临床追综

Clinical Monitoring and Tracing the Middle Cerebral Artery Blood flow Waveforms in 32 Asphyxial Newborn Infants

目的:对32例窒息新生儿大脑中动脉的血流参数进行评估,探讨其临床意义。材料与方法:应用彩色多普勒对32例窒息新生儿和22例正常新生儿大脑中动脉的收缩期峰值速度(Vs)、舒张末期速度(Vd)和阻力指数(RI)进行检测,并对出院后窒息组新生儿行临床追综,追综最长时间60天。结果:试验组患儿24小时内大脑中动脉的Vs、Vd均低于正常对照组,RI高于正常对照组,与正常足月儿比较差异有统计学意义(P<0.05),治疗后试验组新生儿大脑中动脉Vs、Vd升高,RI降低,8-10天后复查各数值与正常对照组比较无统计学意义(P>0.05)。试验组治愈出院新生儿电话随访新生儿一般情况均良好,发育正常。结论:窒息后新生儿脑血流动力学监测对脑损伤早期诊断及预后判断有重要意义。

Purpose： To probe clinical significances by estimate the middle cerebral artery blood flow parameters in 32 asphyxial newborn infants. Materials and Methods： Measuring the systolic peak blood velocity （Vs） , the diastolic blood velocity （Vd） and resistent index （RI） of the middle cerebral artery in 32 asphyxial newborn infants and 22 normal newborn infants by Color Doppler Flow Imaging. And the asphyxial newborn infants were tracked clinically for 60 days longest. Results ： The Vs and Vd was decreasing the RI was increasing in 24 hours, there was a significant difference between experi- mental group and control group （ P 〈 0. 05 ）. The Vs and Vd was increasing the RI was decreasing in experimental group after treatment. And the differences between the two groups was unsigniflcant after 8 to 10 days. （ P 〉 0.05 ）. It was feedbacked by telephone follow-up that those curative newborns in experimental group were well developed. Conclusion： There are impor- tant significances in diagnosing cerebral injury and estimating prognosis by monitoring cerebral artery blood flow waveforms of asphyxiaJ newborn infants.