摘要
[目的]观察黄芪注射液联合腹水回输治疗肝硬化顽固性腹水疗效。[方法]使用随机平行对照方法,将90例住院患者按病志号抽签简单随机分为三组。腹水回输组30例输液泵直接腹水回输,每24h换输血器,引流不畅时改变体位,回输至不能引流出腹水为止,拔出引流管,腹带加压数天,治疗后使用速尿保证尿量>1000m L。黄芪注射液组30例黄芪注射液30m L,常规消毒,左下腹或右下腹部注入腹腔,每隔48h重复注射1次。联合组30例黄芪注射液、腹水回输治疗同腹水回输组与黄芪注射液组。连续治疗14d为1疗程。观测临床症状、血浆白蛋白(ALB)、尿素氮(BUN)、肌酐(Cr),尿量、腹围、体重、不良反应。治疗1疗程,判定疗效。[结果]临床疗效联合组优于腹水回输组(P<0.01),黄芪注射液组与腹水回输组、联合组与黄芪注射液组组间比较无明显差异(P>0.05)。腹围、体重及血浆白蛋白含量各组均有改善(P<0.01),联合组、黄芪注射液组均优于腹水回输组(P<0.01),联合组优于黄芪注射液组(P<0.01)。[结论]黄芪注射液联合腹水回输治疗肝硬化顽固性腹水,疗效满意,无副作用,值得推广。
[Objective] To observe the effect of Huangqi injection combined with ascites back transfusion treatment of intractable aseites due to cirrhosis.[Method] Using random parallel control Method, according to disease Zhihao, draw a simple random divided into three groups of 90 cases of hospitalizedpatients. Ascites reinfusion group 30 cases of transfusion pump directly returning ascites, every 24h to exchange blood transfusion patients, inadequate drainage can change the position, to the drainage of ascites reinfusion not so far, pull out the drainage tube, compression for several days after the treatment, the use of furosemide ensure urine volume〉lOOOmL. Astragalus injection group of 30 cases of Astragalus injection 30mL, regular disinfection, left lower abdominal or lower right abdomen into the abdominal cavity, every 48h repeated 1 times injection. The combined group 30 cases of Astragalus injection, ascites reinfusion treatment with ascites reinfusion group and astragalus injection group. Continuous treatment with 14d for 1 courses. Observation of clinical symptoms, serum albumin (ALB), blood urea nitrogen (BUN), creatinine (Cr), abdominal circumference, urine volume, body weight, adverse reaction. 1 courses of treatment, curative effect.[Results] Clinical effect of combination group is better than the aseites reinfusion group (P〈0.01), Huangqi injection group and reinfusion of ascites group, combination group and astragalus injection group was no difference between the two groups (P〉0.05). Abdominal circumference, body weight and plasma albumin content in each group were impt:oved (P〈0.01 ), combination group, astragalus, injection group was better than the ascites reinfusion group (P〈0.01), combination group is better than that of Astragalus injection group (P 〈0.01). [Conclusion] astragalus injection combined with ascites reinfusion treatment of liver cirrhosis with refractory ascites, satisfactory curative effect, no side effect, is worth promoting.
出处
《实用中医内科杂志》
2015年第3期78-80,共3页
Journal of Practical Traditional Chinese Internal Medicine