子宫腺肌病患病影响因素的logistic回归分析

A Logistic Regression Analysis on Risk Factors of Uterine Adenomyosis

目的分析影响子宫腺肌病发病的影响因素,寻找子宫腺肌病的防治及干预措施,从而减少子宫腺肌病的发病风险。方法 采用病例对照研究的方法 ,以128例患者为实验组,同期入院的非子宫腺肌病的患者256例为对照组。收集可能影响子宫腺肌病的影响因素,包括一般情况、生育及月经情况、生物学指标情况。采用SPSS18.0统计软件进行统计分析,先行单因素因素分析,根据单因素分析有统计学差异的因素进行多因素logistic回归分析。结果单因素分析发现年龄、职业、早产、人工流产次数、剖宫产、痛经、ER、PR和CA125阳性为危险因素。多因素logistic回归分析证实年龄、职业、早产、剖宫产、人工流产次数、FR阳性、ER阳性和CA125阳性为子宫腺肌病的影响因素。结论年龄、职业、早产、剖宫产、人工流产次数、FR阳性、ER阳性和CA125阳性为子宫腺肌病的影响因素,对其危险因素进行干预,可为防治方式提供参考。

Objective To explore the risk factors of uterine adenomyosis （AM）. Methods The case- control study was used to find the risk factors of uterine adenomyosis through the clinical data of 128 patients with uterine adenomyosis in the hos-pital and 256 patients without uterine adenomyosis meanwhile. Data of factors which possibly is involved in uterine adenomyosis were col ected, including general situation, birth and menstruation, biological indicators, was retrospectively analysed to explore risk factors for incidence in patients. First by multivariate analysis , then multiple- factor Logistic regression analysis by SPSS18.0. on statistical y significant factors based on multivariate analysis. Results By single factor analysis, age, occupation, preterm birth, number of induced abortion, cesarean delivery, dysmenorrhea, positive ER, positive FR and positive CA125 were risk fac-tors. Multivariate Logistic regression analysis confirmed that the age, occupation, abortion, premature delivery, cesarean delivery times, FR, ER, and CA125 positive were risk factors of uterine adenomyosis. Conclusion Age, occupation, premature delivery, number of induced abortion, positive FR, positive ER, and positive CA125 were risk factors of adenomyosis and the risk factors intervention, would provide reference for prevention and cure.