阻塞性睡眠呼吸暂停综合征与脑梗死后遗症患者心率变异及血压节律的相关性研究

A study on the correlation of heart rate variability and blood pressure rhythm for patients with obstructive sleep apnea-hypopnea syndrome and sequelae of cerebral infarction

目的：探讨阻塞性睡眠呼吸暂停综合征（OSAHS）与脑梗死后遗症患者心率变异及昼夜血压节律的相关性。方法选取我院2011年10月~2014年1月收治的脑梗死后遗症患者364例，其中伴发OSAHS者178例为伴发OSAHS组，余186例为未见OSAHS组，同期筛选体检健康者180例为健康对照组。观测比较三组昼、夜血压及心率变异等指标。结果伴发OSAHS组患者心率变异及血压节律指标均超过剩余两组（P〈0.01），未见OSAHS组高于健康对照组（P〈0.01）；夜间血氧饱和度比较，伴发OSAHS组比剩余两组低（ P〈0.01）；未见OSAHS组较健康对照组低（P〈0.01）。结论 OSAHS与脑梗死后遗症患者的心率变异、血压节律存在相关性，影响预后，需高度重视。

Objective To explore the correlation of heart rate variability and blood pressure rhythm day and night for patients with OSAHS and sequelae of cerebral infarction. Methods A total of 364 patients with sequelae of cerebral infarction who were admitted to our hospital from October 2011 to January 2014 were selected. 178 patients complicat-ed with OSAHS were assigned to OSAHS group, and the rest of 186 patients were assigned to non-OSAHS group. 180 people with normal results of physical examination during the same period were selected as healthy control group. In-dices such as blood pressure and heart rate variability day and night in the two groups were observed and compared. Results Indices of heart rate variability and blood pressure rhythm were compared, and the indices of patients in OS-AHS group were all much higher than those of the rest two groups （P〈0.01）. Indices of non-OSAHS group were all much higher than those of the healthy control group （P〈0.01）;oxyhemoglobin saturation during the night was compared, and OSAHS group was much lower than the rest two groups （P〈0.01）; oxyhemoglobin saturation in non-OSAHS group was lower than that in healthy control group （P〈0.01）. Conclusion OSAHS and sequelae of cerebral infarction are cor-related with heart rate variability and blood pressure rhythm, which affect the prognosis and needs to be attached high importance.