腰大池持续引流脑脊液与腰穿释放脑脊液对蛛网膜下腔出血患者预后比较的meta分析

Lumbar continued drainage and lumbar puncture for patients with sub-arachnoid hemorrhage: A meta-analysis

目的系统评价腰大池持续引流脑脊液(LCD)和腰穿释放脑脊液(LP)对蛛网膜下腔出血(SAH)患者的预后比较。方法计算机检索中文、外文数据库,纳入所有关于LCD/LP的随机对照试验,并对纳入文献进行质量评价。数据统计分析采用Rev Man 5.0软件进行。结果最后有19个随机对照试验(RCT)符合标准,患者共计1898例。Meta分析结果显示:依GOS预后评分,恢复良好率LCD优于LP;并发症发生率LCD低于LP。结论在掌握其适应证情况下,LCD更加安全有效。

Objective To assess the effect of lumbar continued drainage （LCD） and lumbar puncture （LP） for patients with subarachnoid hemorrhage （SAH）. Methods Searched Chinese and foreign databases, the randomized controlled tri-als（RCTs） about LCD/LP were included. The quality of the articles was assessed. The data was input and analyzed by RevMan 5.0 software. Results Nineteen randomized controlled trials（RCTs） （1898 patients） met the inclusion criteria. Meta analysis results showed according to GOS prognostic score, well recovery rate of LCD was better than that of LP, complication rates of LCD were lower than that of LP. Conclusion In mastering its indicatio cases, LCD is more safe and effective.