髓心减压植骨术联合通痹益肾汤治疗股骨头坏死的效果观察

Medullary Core Decompression and Bone Grafting Combined with Tongbi Decoction for Tonifying Kidney Therapy To Observe the Effect of Avascular Necrosis of the Femoral Head

目的:探讨髓心减压植骨术联合通痹益肾汤治疗股骨头坏死的临床疗效。方法:将60例股骨头坏死患者随机分为治疗组和对照组两组,每组各30例,两组患者在接受一般治疗的同时,对照组采用髓心减压植骨术治疗,术手配合口服磷酸川芎嗪片。治疗组在手术治疗的基础上还结合中药通痹益肾汤口服。两组治疗疗程均为8周,所有患者治疗结束后统计相关观察指标。结果:治疗结束后,治疗组与对照组临床总有效率分别为96.7%、73.3%,两组相比,有显著性差异(P<0.05)。治疗后,治疗组与对照组FPS-R评分分别为(0.96±0.80)、(2.41±1.56),均较治疗前明显下降,但治疗组下降程度明显优于对照组,两组相比,有统计学差异(P<0.05)。两组治疗后在Harris评分的比较中,治疗组为(90.53±8.42),对照组为(81.38±9.25),治疗组评分明显高于对照组,两组相比,有显著性差异(P<0.05)。在两组治疗后生存质量评分(SF-36量表评分)的比较中,治疗治疗组为(8.53±1.42),对照组为(6.38±1.65)治疗组评分明显高于对照组,两组相比,有显著性差异(P<0.05)。两组患者的平均住院时间治疗组亦明显短于对照组,两组相比,有统计学差异(P<0.05)。结论:通过髓心减压植骨手术后配合中药通痹益肾汤口服治疗股骨头坏死不但可以明显提高本病的临床疗效,还可以减少患者的临床痛苦,改善术后患者的生活质量,而且没有明显的不良反应,效果明显仍优于对照组,值得临床推广使用。

Objective： To investigate the clinical effect of intramedullary decompression bone grafting combined Tongbi Yishen Decoction in the treatment of avascular necrosis of the femoral head. Methods ： 60 cases of avascular necrosis of the femoral head were randomly divided into treatment group and control group two groups, 30 cases in each group, two groups of patients in general treatment at the same time, the control group using intramedullary decompression bone graft- ing for the treatment of patients with oral, hand Ligustrazine Phosphate Tablets. In the treatment group based on operation therapy combined with Chinese medicine Tongbi Decoction for tonifying kidney oral. The treatment course of two groups was 8 weeks, the end of all patients after the treatment of statistical correlation observed index. Results： after the treat- ment, the treatment group and the control group, the clinical total effective rate were 96.7%, 73.3%, compared to the two groups, there was significant difference （ P 〈 0. 05 ）. After the treatment, the treatment group and the control group respectively （ FPS - R score O. 96 ± 0.80）, （2.41 ± 1.56）, were significantly decreased than before, but the treatment group decreased significantly than that of the control group, the two groups were compared, there were significant differ- ences （ P 〈 0. 05 ）. Comparison of the two groups after treatment in Harris score, treatment group （90.53 ± 8.42 ）, con- trol group （81.38 ＋ 9.25）, the treatment group was significantly higher than that in the control group, the two groups were compared, there was a significant difference （ P 〈 0.05 ）. Quality of life scores in the two groups after treatment （ SF -36 scale） in the comparison of treatment, treatment group is （8.53 ± 1.42）, control group （6.38 ± 1.65） in treat- ment group were significantly higher than the control group, the two groups were compared, there was a significant differ- ence （ P 〈 0.05 ）. The average hospitalization time of two groups of patients in treatment group was obviously shorter than that in the control group, the two groups were compared, there were significant differences （ P 〈 0. 05 ）. Conclusion ： bone graft operation through the pith decompression combined with traditional Chinese medicine Tongbi Yishen Decoction oral treatment of avascular necrosis of the femoral head not only can significantly improve the clinical efficacy of the disease, but also can reduce the clinical pain of patients, improve the quality of life of patients after operation, and no obvious tox- ic side effect, obvious effect is better than that of the control group, it is worth clinical use.