102例老年重症心力衰竭的内科治疗的临床分析

Medical treatment of severe heart failure in the elderly: a clinical analysis of 102 cases

目的研究内科治疗老年重症心力衰竭患者的临床治疗效果。方法以我院2012年5月至2014年5月期间收治的102例老年重症心力衰竭患者临床病例为研究者对象,将其随机分对照组和干预组,每组51例患者。对照组患者在临床治疗中仅给予常规的心力衰竭药物治疗(强心剂、利尿剂、硝普钠),干预组在常规治疗的基础上给予美托洛尔片联合厄贝沙坦氢氯噻嗪片药物进行辅助治疗,对比两组患者的治疗效果。结果干预组临床治疗效果总有效率明显高于对照组,差异具有统计学意义(P<0.05),同时治疗后对照组和干预组两组患者在心率(HR)、左心室射血分数(LVEF)、收缩压值(SBP)、舒张压值(DBP)指标方面有差异统计学意义(P<0.05)。结论临床内科治疗老年重症心力衰竭,在采用常规利尿剂、强心剂的基础上,联合应用尔厄贝沙坦氢氯噻嗪与美托洛尔可以有效提高老年重症心力衰竭患者的治疗率,显著改善患者的心脏功能,最大化提高患者的生存率。

Objective To investigate the response to medical treatment in elderly patients with severe heart failure. Methods This study included 102 elderly patients with severe heart failure admitted to the Fourth People＇s Hospital of Zhumadian from May 2012 to May 2014. These patients were randomly divided into control and treatment groups, each with 51 cases. The control group received the routine drug therapy （cardiotonic, diuretic, and sodium nitroprusside）, while the treatment group received adjuvant therapy with metoprolol tablets combined with irbesartan and hydrochlorothiazide tablets in addition to the routine drug therapy. The efficacy was compared between the two groups. Results The overall response rate was significantly higher in the treatment group than in the control group （P〈0.05）. In addition, significant differences between the control and treatment groups were also observed in heart rate, left ventricular ejection fraction, systolic pressure, and diastolic pressure （P〈0.05）. Conclusion In addition to the routine drug therapy with diuretic and cardiotonic, metoprolol tablets combined with irbesartan and hydrochlorothiazide tablets can increase the overall response rate, improve the heart function, and increase the survival rate in elderly patients with severe heart failure.