1Yeo SG, Kim DY, Kim TH, et al. Pathologic complete response of primary tumor following preoperative chemoradiotherapy for local- ly advanced rectal cancer:long-term outcome and prognostic sig- nificance of pathologic nodal status ( KROG09-01 ) [ J ]. AnnSurg,2010,252 ( 6 ) :998 - 1004.
2Lu JY, Xiao Y, Qiu HZ, et al. Clinical outcome of neoadjuvant chemoradiation therapy with oxaliplatin and capecitabine or 5- fluorouracil for locally advanced rectal cancer~ J]. J Sorg On- col,2013,108(4) :213 -219.
3Korkeila E, Jaakkota PM, Syjane K, et al. Preoperative radio- therapy down regulates the nuclear expression of hypoxia-induc- ible factor-lalpha in rectal cancer[ J]. Seand .} Gastroenlenrol, 2010,45 ( 3 ) : 340 - 348.
4Sebag-Montefiore D, Meadows HM, Cunningham D, et al. Three cytotoxic drugs combined with pelvic radiation and as mainte- nance chemotherapy for patients with squamous cell carcinoma of the anus(SCCA) long-term follow-up of a phase II pilot study using 5-f/uorouracil. mitomycln C and cisptatin [ J ]. Radiother Oncol,2012,104(2) :155 - 160.
5Crane CH,Eng C,Feig BW, et ai. Phase H trial of neoadjuvant bevacizumad, capecitabine, and radiotherapy for locally advanced resectsble cancer [J]. lnt J Radiat Oncol Biol Phys, 2010,76 (3) :824 -830.
8Jung SH, Heo SH, Kim JW, et al. Predicting response to neoadju- vant chemoradiation therapy in localtyadvanceed rectal cancer: diffusion-weighted 3 Tesla MR imaging[ J]. J Magn Reson Ima- ging,2012,35(1 ) :110 - 116.
9Barbaro B, Vitale R, Valentini V, et al. Diffusion-weighted mag- netic resonance imaging in monitoring rectal cancer response to neoadjuvant chemoradiotherapy [ J ]. Int J Radiat Oncol Biol Phys, 2012,83 ( 2 ) : 594 - 599.
10Kim SH, Lee JY, Lee JM, et al. Apparent diffusion coefficient for evaiuating tumour response to neoadjuvant chemoradiation therapy for locallyad vanceed rectal cancer [ J ]. Eur Radiol, 2011,21 (5) :987 -995.
2Abdulamir AS, Hafidh RR, Abubakar F. Different inflammatory mechanisms in lungs of severe and mild asthma: crosstalk of NF- kappa-B, TGFbetal, Bax, Bcl-2, IL-4 and IgE. Scand J Clin Lab Invest, 2009, 69: 487-495.
3Cory S, Huang DC, Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene, 2003, 22: 8590-8607.
4Meng XW, Lee SH, Kaufmann SH. Apoptosis in the treatment of cancer: a promise kept? Curr Opin Cell Biol, 2006, 18: 668- 676.
5Zhang YL, Pang LQ, Wu Y, et al. Significance of Bcl-XL in human colon carcinoma. World J Gastroenterol, 2008, 14: 3069- 3073.
6Muchmore SW, Sattler M, Liang H, et al. X-ray and NMR structure of human Bcl-XL, an inhibitor of programmed cell death. Nature, 1996, 381: 335-341.
7Sattler M, Liang H, Nettesheim D, et al. Structure of Bcl-XL-Bak peptide complex: recognition between regulators of apoptosis. Science, 1997, 275: 983-986.
8Gallenne T, Gautier F, Oliver L, et al. Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members. J Cell Biol, 2009, 185: 279-290.
9Yang WL, Addona T, Nair DG, et al. Apoptosis induced by cryo- injury in human colorectal cancer cells is associated with mitochondrial dysfunction. Int J Cancer, 2003, 103: 360-369.
10Paradiso A, Simone G, Lena MD, et al. Expression of apoptosis- related markers and clinical outcome in patients with advanced colorectal cancer. Br J Cancer, 2001, 84: 651-658.
3Gallagher M J,Brereton H D,Rostock R A,et al.A prospective study of treatment techniques to minimize the volume of pelvic small bowel with reduction of acute and late effects associated with pelvic irradiation[J].Int J Radiat Oncol Biol Phys,1986,2:1565.
4Glimelius B,Isacsson U,Jung B,et al.Radiotherapy in addition to radical surgery in rectal cancer:evidence for a doseresponse effect favoring preoperative treatment[J].Int J Radiat Oncol Biol Phys,1997,37:281.
5Greer P B,Mortensen T M,Jose C C.Comparison of two methods for anteriorposterior isocenter localization in pelvic radiotherapy using electronic portal imaging[J].Int J Radiat Oncol Biol Phys,1998,41:1193.
6Lammering G,Hartmann K A,Frenken M,et al.Shortterm hypofractionate radiotherapy followed by total mesorectal excision[J].Strahlenther Onkol,2000,176(12):555.
7Grrard J P,Azria D,Gourgou-Bourgade S,et al.Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer:results of the phaseⅢtrial ACCORD 12/0405-Prodige 2[J].J Clin Oncol,2010,28(10):1638.
8Kim T H,Kim D Y,Cho K H,et al.Comparative analysis of the effects of belly board and bladder distension in postoperative radiotherapy of rectal cancer patients[J].Strahlenther onkol,2005,181(9):601.
9Sauer R,Fietkau R,Wittekind C,et al.Adjuvant versus neoadjuvant radiochemo-therapy for locally advanced rectal cancer.A progress report of a phase-Ⅲrandomized trial(protocol CAO/ARO/AIO-94)[J].Strahlenther Onkol,2000,177:173.
10Shanahan T G,Mehta M P,Bertelrud K L,et al.Minimization of small bowel volume within treatment fields utilizing customized"belly boards"[J].Int J Radiat Oncol Biol Phys,1990,19:469.
