摘要
目的探讨中医优化方案治疗非酒精性脂肪性肝炎(NASH)的临床疗效。方法选择NASH患者104例,随机分为观察组与对照组,各52例。对照组予以多烯磷脂酰胆碱胶囊治疗,观察组予以化痰利湿活血方基本方颗粒剂联合加减方颗粒剂治疗,比较2组的临床疗效。结果治疗后观察组的谷丙转氨酶(ALT)及甘油三酯(TG)分别为(35.49±18.33)mmol/L、(1.60±0.87)mmol/L,均显著低于对照组的(53.94±41.42)mmol/L、(2.02±1.15)mmol/L(P<0.05),观察组肝脾CT值为(0.99±0.18)HU,显著高于对照组的(0.82±0.21)HU(P<0.05);观察组的证候积分为(3.69±3.21)分,显著低于对照组的(8.01±5.78)分(P<0.05);观察组的治疗总有效率为98.1%,显著高于对照组的80.8%(P<0.05)。结论中医优化方案治疗NASH疗效显著。
Objective To investigate the clinical efficacy of traditional Chinese medicine optimization program for the treatment of patients with non-alcoholic steatohepatitis (NASH). Methods 104 NASH patients were randomly divided into observation group and control group, 52 cases in each. The control group received polyene phosphatidylcholine capsule treatment, the observation group received Huatan Lishi Huoxue granule combined granule decoction treatment, the clinical efficacy of two groups were compared. Results After treatment,the ALT and TG of the observation group was (35.49±18.33)mmol/L, (1.60±0.87)mmol/L, significantly lower than (53.94±41.42)mmol/L and (2.02±1.15)mmol/L of the control group (P〈0.05), the liver and spleen CT value of the observation group was (0.99±0.18)HU, significantly higher than the (0.82±0.21)HU of control group (P〈0.05); the symptom score of the observation group was (3.69±3.21), significantly lower than the (8.01±5.78) of control group (P〈0.05); the total efficiency of observation group was 98.1%, significantly lower than 80.8% in the control group (P〈0.05). Conclusion Traditional Chinese medicine optimization program for the treatment of NASH has a significant effect
出处
《当代医学》
2015年第13期152-153,共2页
Contemporary Medicine
关键词
非酒精性脂肪性肝炎
中医
临床疗效
Nonalcoholic steatohepatitis
Traditional Chinese medicine
Clinical efficacy