老年冠心病疗养员血脂相关性心血管剩留风险调查分析

Diagnoses of blood lipid related residual cardiovascular risks among aged convalescents with coronary heart disease

目的了解老年冠心病疗养员降脂药物治疗现状及血脂参数水平,评估该人群血脂相关性心血管剩留风险。方法共入选老年冠心病疗养员362例,收集降脂药物治疗情况并测量血清总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)等血脂参数,计算脂代谢异常发生率。结果老年冠心病疗养员中,单独服用他汀类药物者345例,单独服用贝特类药物者0例,联合服用他汀类及贝特类药物者17例。高胆固醇血症、高三酰甘油血症、高低密度脂蛋白胆固醇血症、低高密度脂蛋白胆固醇血症的患病率分别是9.94%(36/362)、18.23%(66/362)、5.80%(21/362)、16.57%(60/362)。结论老年冠心病疗养员存在不同程度的脂代谢异常,在关注强化降脂治疗的同时,应加强心血管剩留风险评估并进行干预,尽早、全面地纠正血脂异常,从而最大程度地降低老年冠心病疗养员心血管剩留风险。

Objective To study the lipid-low ering drug therapy status and the level of blood lipid param eters of aged convalescents with coronary heart disease and estim ate the blood lipid related residual cardiovascular risks of el-derly convalescents.Methods 362 aged convalescents with coronary heart disease w ere selected to collect lipid-low er-ing drug therapy status and m easure total cholesterol （TC ）,triglyceride （TG ）,low density lipoprotein cholesterol （LDL-C）,high density lipoprotein cholesterol（HDL-C ）and other lipid param eters,then to calculate the incidence of dys-lipidem ia.Results In aged convalescents with coronary heart disease,345 cases took statins alone,0case took fibrates alone,and 17 cases took statins and fibrates.The prevalence rates of hypercholesterolem ia,hypertriglyceridem ia,high LD L-C cholesterol,low HDL-C cholesterolw ere 9.94% （36/362）,18.23% （66/362）,5.80% （21/362）,and 16.57% （60/362）. Conclusion There are varying degrees of dyslipidem ia in aged convalescents with coronary heart disease.We should intensify lipid-low ering therapy and strengthen residual cardiovascular risk assessm ent and intervention,correct dyslipi-dem ia as early and com pletely as possible,so as to m inim ize the residual cardiovascular risks in aged convalescents with coronary heart disease.