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ABCD3-I评分对短暂性脑缺血发作病人近期脑梗死风险的评估 被引量:14

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摘要 目的评估ABCD3-I评分对短暂性脑缺血发作(TIA)后近期发生脑梗死风险的预测价值。方法选取山西省心血管病医院神经内科2011年1月—2013年1月200例确诊为短暂性脑缺血发作病人的临床资料,所有病人均于发病后72 h内行头颈部CT血管造影(CTA)检查和头颅磁共振扩散加权成像(DWI),采用ABCD3-I评分法分为低危组、中危组和高危组,观察TIA后7 d、90 d内各组脑梗死的发生率。并比较ABCD2评分法、ABCD3-I评分法的阳性预测值。采用Logistic回归模型预测TIA后早期进展为脑梗死的危险因素。结果低危组、中危组、高危组7 d内脑梗死发生率分别为0、2.8%、32.9%,90 d内卒中发生率分别为0、5.6%、52.9%。与低危组、中危组比较,高危组TIA后7 d、90 d内脑梗死发生率明显升高(P〈0.01)。中危组与低危组比较,中危组90 d内脑梗死发生率升高(P〈0.01)。预测7 d内脑梗死发生风险时:ABCD2评分法、ABCD3-I评分法的曲线下面积分别为0.840、0.901。预测90 d脑梗死发生风险时:ABCD2评分法、ABCD3-I评分法的曲线下面积分别为0.792、0.862。Logistic回归模型显示,DWI检查出现高信号病人90 d内预测卒中风险OR值为1.101,95%CI 27.710-221.34,P〈0.01;同侧颈动脉中重度狭窄病人90 d内预测卒中风险OR为7.601,95%CI 2.076-29.320,P〈0.01。结论高危病人7 d及90 d内脑梗死发生率均升高。中危病人90 d内脑梗死发生率升高。ABCD3-I评分法预测短暂性脑缺血发作后脑梗死风险时优于ABCD2评分法。DWI检查出现高信号、同侧颈动脉中重度狭窄与TIA后早期发生脑梗死相关。
出处 《中西医结合心脑血管病杂志》 2015年第4期474-477,共4页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金 山西省科技攻关项目(No.20120313018-10)
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参考文献14

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二级参考文献40

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