萃取精馏分离甲醇-乙酸乙酯的模拟研究

Simulation study of the separation of methanol and ethyl acetate in pharmaceutical waste liquid by extractive distillation

通过Aspen Plus化工流程模拟软件,利用萃取精馏法,以二甲基亚砜(DMSO)为萃取剂,对甲醇-乙酸乙酯共沸物进行了分离模拟研究。确定最优工艺参数为:萃取精馏塔理论板数41,混合物进料位置25,萃取剂进料位置4,回流比2.1,溶剂比3.8;溶剂回收塔理论板数12,进料位置7,回流比0.7。萃取精馏塔塔顶乙酸乙酯质量分数达99.80%,溶剂回收塔塔顶甲醇质量分数达99.74%。对分离过程优化操作及设计提供了理论依据。

The extractive distillation separation process of the azeotropic system of methanol and ethyl acetate is simulated using chemical process simulation software Aspen Plus,and dimethyl sulfoxide（DMSO） is chosen as extractive agent. The optimal condition of the extractive distillation process is as follows： in the extractive distillation column, the number of theory stage is 41, the mixture feed stage is 25, the extractive agent feed stage is 4, reflux ratio is 2.1, the ratio of extractive agent is 3.8, in the solvent recovery colfimn, the number of theory stage is 12, the feed stage is 7, reflux ratio is 0.7. The mass fraction of ethyl acetate is 99.80% at the top of extractive distillation column, the mass fraction ofmethanol is 99.74% at the top of sol- vent recovery column. The results can provide theory evidence for optimization operation and design of the separation process.