神经电生理监测对重症脑血管病脑功能预后评估

Evaluation of neurophysiological examination for cerebral function prognosis in severe cerebrovascular disease

目的探讨脑电图、体感诱发电位及脑干听觉诱发电位监测对重症脑血管病脑功能预后的评价。方法在入院24 h内对重症脑血管病患者进行脑电图、体感诱发电位、脑干听觉诱发电位监测。以发病后3个月或3个月死亡为观察终点,追踪患者的脑功能预后。分析脑电图、体感诱发电位及脑干听觉诱发电位监测结果与脑功能预后之间的关系。结果有序logistic回归分析发现脑电图(P=0.002)、体感诱发电位(P<0.001)、脑干听觉诱发电位(P=0.002)监测对重症脑血管病患者脑功能预后的影响显著。结论利用脑电图、体感诱发电位、脑干听觉诱发电位联合的监测方法可以对重症脑血管病患者脑功能进行预后预测,对于重症脑血管病患者的病情估计、预后判断和诊断治疗具有重要意义。

Objective To investigate the value of electroencephalography, somatosensory evoked potential and brainstem auditory evoked potential on the evaluation of cerebral function of patients with severe cerebrovascular disease. Methods In 24 hours after admitted to hospital, the patients with severe cerebrovascular disease were examined by electroencephalography, somatosensory evoked potential and brainstem auditory evoked potential. The prognosis of cerebral function were evaluated 3 months after the onset of severe cerebrovascular disease or when the patients died in 3 months. Analyze the relationships between the results of the exams above and cerebral function prognosis. Results Ordinal logistic regression analysis found that electroencephalography（P=0.002）, somatosensory evoked potential（P 〈 0.001） and brainstem auditory evoked potential（P=0.002） have a signiifcant effect on the prediction of cerebral function prognosis of severe cerebrovascular disease patients. Conclusion By using electroencephalography, somatosensory evoked potential and brainstem auditory evoked potential exams can make a prediction of prognosis of severe cerebrovascular disease. This is of great importance in evaluating the illness, predicting prognosis, diagnosing and treating severe cerebrovascular disease.