中医药治疗肠易激综合征用药规律分析

Analysis of Using Drugs Regularity in Treating Irritable Bowel Syndrome by TCM

目的:分析基于1994—2013年期刊文献的中药治疗肠易激综合征用药规律。方法:将收集到的486篇中医药治疗肠易激综合征文献录入到Microsoft Access 2010数据库中,运用Microsoft Excel数据透视表对其进行统计分析。将肠易激综合征中药治疗分为辨证治疗与专方治疗两大类,每类又分为肠易激综合征综合型、腹泻型与便秘型3个亚型,分别统计分析其处方用药规律,并与最新中医诊疗标准进行比较。结果:肠易激综合征腹泻型发病以脾虚为核心病机,肠易激综合征便秘型发病则以大肠津亏为核心病机,肠易激综合征综合型兼顾腹泻型与便秘型,但辨证处方用药的针对性不及前两者。肠易激综合征专方治疗文献的辨证分型不全,用药方面可以补充辨证治疗的不足。如肠易激综合征腹泻型患者罹病日久,健脾渗湿法多有不应,止泻常用固涩、温阳之品;肠易激综合征便秘型患者用药常酌加种子或果仁类药物,取其润肠通便之效。结论:通过与目前肠易激综合征中医诊疗标准比较,辨证分型、处方、用药3个方面均存在一定差异。

Objective：Analysis of using drugs regularity in treating irritable bowel syndrome by TCM was based on 1994 -2013 the jour- nal of Chinese medicine. Methods：The collected 486 articles about irritable bowel syndrome by TCM enter into Microsoft Access 2010 database, using Microsoft Excel pivot tables for statistical analysis. Irritable bowel syndrome by TCM therapy will be divided into syn- drome differentiation and treatment, special treatment. Each category is divided into comprehensive type, diarrhea type and constipation type. statistical analysis of the prescription medication rule respectively, and comparing with the latest standard of TCM diagnosis and treatment. Results ： The main pathogenesis is spleen deficiency in diarrhea type. Fluid deficiency is the main pathogenesis of constipation type. Synthesizing type considerates diarrhea and constipation, but the pertinence is not as good as the first two. The differentiation and treatment of literature type about irritable bowel syndrome is not complete, drugs can supplement the diagnosis deficiency. Eg ： The pa- tients of diarrhea type for a long time which can not improved by tonifying spleen and excreting dampness. Using the drugs of inducing astringency and warming Yang have good curative effect. The patients of constipation type should have drugs of seeds and nutlets for re- laxing bowel. Conclusion：The syndrome differentiation,prescription, drug are all exist certain differences by comparison with the treat- ment standards of irritable bowel syndrome by TCM theropy.