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缺血性脑血管病患者脑微出血危险因素及与认知功能的相关性 被引量:14

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摘要 目的探讨缺血性脑血管病患者脑微出血(CMBs)的危险因素及其对认知功能的影响方法 183例缺血性脑血管病患者依据头部MRI梯度回波T2加权像分为CMBs组(66例)和Non-CMBs组(117例),观察2组患者的一般资料、并发症及腔隙性梗死数目和脑白质疏松程度,并进行蒙特利尔认知评估(MoCA)量表评分。结果 CMBs组患者平均年龄大于Non-CMBs组患者(72.9±5.3vs 69.6±4.9,t=4.25,P<0.001);CMBs组患者腔隙性脑梗死数目和脑白质疏松程度均高于Non-CMBs组(3.98±0.85vs 3.05±0.77,t=7.55,P<0.001;4.91±1.02vs 3.67±0.74,t=9.46,P<0.001);高血压(OR=2.324)、年龄(OR=1.118)、腔隙性梗死数目(OR=1.645)及脑白质疏松程度(OR=2.347)为CMBs的危险因素;CMBs患者MoCA评分低于Non-CMBs患者(22.41±2.30vs 24.22±2.48,t=4.86,P<0.001),分别在视空间执行能力、命名、注意和定向4个维度中差异有统计学意义(P<0.05)。结论年龄、合并高血压、腔隙性梗死数目和脑白质疏松程度为CMBs的独立危险因素,CMBs患者伴随一定程度的认知功能障碍。
作者 张晓燕
出处 《中国实用神经疾病杂志》 2015年第5期58-60,共3页 Chinese Journal of Practical Nervous Diseases
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