232例次单采血小板输注疗效的分析

Analysis on effect of apheresis platelets transfusion in 232 case-times

目的探讨无交叉配型的单采血小板(PLT)临床输注后的效果及疗效。方法通过对输注单采PLT的患者进行输注前及输注后1h和24h外周血PLT计数,对单采PLT输注效果进行评价。结果输注单采PLT的患者与输注前相比,PLT总体上有明显提高,平均有效率达72.41%(168/232)。有输注PLT史的患者与普通患者相比,输注PLT有效率随着次数增加而降低,不同输注次数总体组间差异有统计学意义(χ2=37.89,P<0.05)。结论临床医生应该严格控制患者输注PLT指征、掌握患者情况,减少或避免输注无效的发生,提高PLT输注有效率及临床疗效。

Objective To investigate the effects and clinical efficacy of non-erossmateh apheresis platelets（PLT） transfusion. Methods Peripheral blood PLT count was performed before transfusion and at 1,24 h after transfusion in the patients with apheresis PLT transfusion for evaluating the effect of apheresis PLT transfusion. Results Compared with before transfusion, the PLT count in the patients with apheresis PLT transfusion was significantly increased as a whole, the average effective rate reached 72.41 % （168/232）. In the comparison between the patients with PLT transfusion history and the common patients, the effective rate of PLT transfusion was decreased with the frequency increase. The difference among different PLT transfusion frequencies had statistical significance（x2=37.89 ,P〈0.05）. Conclusion Clinicians should strictly control the indications of the patients with PLT transfusion,grasp the patient＇s condition,reduce or avoid the occurrence of invalid transfusion in order to improve the efficiency of PLT transfusion and clinical efficacy.