徐氏痛经松方治疗子宫内膜异位症痛经临床及实验研究

Research of Treatment to Endometriotic Dysmenorrhea by Prescription of “Xu Shi Tong Jing Song”

目的:研究徐氏痛经松方治疗气滞血瘀型子宫内膜异位症痛经患者的疗效。方法:选取2012年8月—2013年12月于安徽中医药大学第一附属医院妇科就诊的中医辨证为气滞血瘀型痛经,西医明确诊断为子宫内膜异位症痛经的患者76例。所有患者随机分为两组,A组38例患者口服痛经松方,B组38例患者口服中成药,治疗3个月后均进行疗效评定。结果:痛经松方治疗组患者的痛经程度及中医证候评分均得到明显改善,A组总体有效率为92.1%,明显优于B组(57.9%),两组患者治疗后血清CA125及Em Ab水平均明显下降。结论:徐氏痛经松方在治疗子宫内膜异位症方面具有一定优势,能够明显改善症状,提高总体疗效,同时可以降低相关血清标志物水平。

Objective ： To investigate the treatment effect of the Xushi Tongjingsong Prescription in endometriotic dysmenorrhea caused by qi stagnancy and blood stasis. Methods： Seventy-six patients of endometriotic dysmenorrhea caused by qi stagnancy and blood stasis were selected from 2012.8 to 2013.12 in the department of gynecology of 1st affiliated hospital of anhui traditional Chinese medical university. All patients were divided into 2 groups randomly, group A （ 38 cases ）were treated with the Xushi Tongjingsong Prescription, as well as group B （ 38 cases ）were treated with Chinese patent medicine. Results of two groups were evaluated after 3 months. Results ： The degree of dysmenorrhea and grade in group A were ameliorated. The total effective ratio in group A was 92.1%, which is better than group B （ 57.9% ）. The serum level of CA125 and EmAb decreased obviously in both groups. Conclusions ： The Xushi Tongjingsong Prescription has some advantages in the treatment of endometriotic dysmenorrhea by ameliorating symptoms, improving total therapeutic effect and decreasing the serum level of certain mark protein.