老年神经内科患者院内感染临床分析及防控研究

Clinical analysis and the control research of efficacy in elderly patients with hospital-acquired infection in the department of neurology

目的探讨老年神经内科院内感染的影响因素,并总结防控对策,以期提高临床治疗水平。方法选取2010-01—2013-01我院收治的110例老年神经内科院内感染患者为研究对象,运用抗生素等规范治疗,观察预后的影响因素,并进行全面干预,观察干预前后在满意度等方面的变化。结果老年神经内科院内感染的影响因素也是独立危险因素有神经性病变、并发症、白细胞计数(≥20×109个/L)、住院时间(≥14d)、累及间隙数量(>2个)、细菌生长、联合应用抗生素等(P<0.05);与患者性别、年龄、累及间隙位置无关(P>0.05)。而干预前后在感染数、满意度、依从性和病原菌上比较有显著差异(P<0.05)。结论影响老年神经内科院内感染和疾病本身、医护无菌操作等有紧密关系,加强干预有助于控制感染。

Objective To investigate the affecting factors of efficacy in elderly patients with hospital-acquired infection in the department of neurology and summarize the strategies of prevention and control,in order to improve the level of clinical treatment.Methods One hundred and ten elderly patients with hospital-acquired infection from January 2010 to January 2013 in the department of neurology were selected as study subjects,which were treated with antibiotics and other standardized therapy,observing the affecting factors of prognosis,conducting comprehensive interventions and detecting the changes of satisfaction before and after intervention.Results The independent risk factors of efficacy in elderly patients with hospital-acquired infection in the department of neurology included neuropathy,complications,leucocyte counts（≥20×10^9/L）,in-hospital stays（≥14d）,the number of involved gaps（〉2）,bacterial growth and combination with antibiotics（P〈0.5）;and factors were unrelated to sex,age,and gap position（P〉0.5）.After treatment the number of infections,satisfaction,compliance,and pathogens all showed significant differences compared with before intervention（P〈0.5）.Conclusion The affecting factors of efficacy have closely connection with disease itself and aseptic operation,and intensive interventions help to control the infection.