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肌内注射NGF对新生儿缺氧缺血性脑病智力发育指数的影响

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摘要 目的探讨肌内注射神经生长因子(nerve growth factor,NGF)对新生儿缺氧缺血性脑病智力发育指数(mental development index,MDI)的影响。方法新生儿缺氧缺血性脑病患者中随机选择80例随机分为2组,分别实施常规治疗和肌内注射NGF。监测2组的MDI,并进行比较。结果所有患儿均获得随访,随访率100.0%。随访结果显示,自3个月起,2组MDI均显著上升,观察组在6~12个月上升最为明显,对照组上升幅度较观察组除3个月无显著差异外,其余月份均显著低于对照组(P〈0.05)。结论在常规治疗的基础上,联合使用肌内注射神经生长因子(NGF)治疗新生儿缺氧缺血性脑病可以有效改善患儿的智力发育情况。
作者 唐瑜
出处 《中国实用神经疾病杂志》 2015年第8期116-117,共2页 Chinese Journal of Practical Nervous Diseases
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