从“毒损脑络”探讨血管性痴呆的机理

Discussion of the Pathogenesis of Vascular Dementia From "Toxin Impairing Brain Collaterals"

血管性痴呆(Vaseular Dementia,VD)确切的发病机制尚不清楚,众医家提出"毒损脑络"假说,并通过大量临床与实验研究发现中医药治疗VD取得明显疗效,其中解毒补肾活血法应用最多。从毒损脑络理论探讨中医药治疗VD机制的研究,将为中医药对该病的防治提供必要的理论依据。但目前细胞生物学方面的研究还不多见,应加强此方面的研究。

The exact pathogenesis of vascular dementia （VD） is not clear. Many physicians have proposed the hypothesis of ＂toxin impairing brain collaterals＂ and discovered that traditional Chinese medicine （TCM） has remarkable effect on VD tln＇ough a lot of clinical and experimental researeh,among which the method of ＂removing toxin,tonifying the kidney and activating blood flow＂ is the most commonly applied. The research on the pathogenesis of VD explored from ＂toxin impairing brain collaterals＂ in TCM will provide necessary theoretical basis for the treatment of VD by Chinese medicine. However, the current research on cytobiology is far from enough ,therefore it should be valued.