左归汤加减治疗中老年顽固性失眠40例

40 Cases of Middle-aged and Elderly Patients with Intractable Insomnia Treated by Modified Left-Restoring Decoction

目的:观察左归汤加减治疗中老年顽固性失眠的临床疗效。方法:选取老年顽固性失眠患者80例,随机分为对照组和观察组各40例。对照组给予阿普唑仑口服治疗,观察组在对照组治疗的基础上加用左归汤加减治疗。结果:观察组有效率为97.5%,对照组有效率为80.0%,观察组优于对照组(P<0.05);观察组治疗后匹兹堡睡眠质量指数评分均显著低于对照组(P均<0.05);两组患者均未发生明显的不良反应。结论:左归汤加减治疗中老年顽固性失眠临床疗效显著,可显著改善患者的睡眠质量。

Objective ：To observe the clinical effect of modified Left-Restoring Decoction on middle-aged and elderly patients with intractable insomnia. Methods ：80 cases with senile intractable insomnia were randomized into control group and treatment group, with 40 cases in each group. Control group were orally given alprazolam and observation group were additionally given modified Left-Restoring Decoction. Results：The effective rate of observation group was 97.5% while that of control group was 80.0% ;ob- servation group were better than control group （P 〈 0.05 ）. The pittsburg sleep quality index （PSQI） score in observation group was obviously lower than that in control group （ P 〈 0.05 ）. Patients in both groups appeared no obvious adverse reactions. Conclu- sion ： Modified Left-Restoring Decoction has remarkable effect on middle-aged and elderly patients with intractable insomnia, which can significantly improve the sleep quality of the patients.