中西医结合治疗功能性消化不良68例

68 Cases with Functional Dyspepsia Treated with Therapy of Integrative Chinese and Western Medicine

目的:观察中西医结合治疗功能性消化不良的临床疗效。方法:将135例功能性消化不良患者随机分为对照组67例和观察组68例。对照组给予西沙必利和奥美拉唑肠溶胶囊治疗,观察组在对照组治疗的基础上给予自拟和胃消痞汤治疗。结果:对照组有效率为73.1%,观察组有效率为91.2%,两组有效率比较,差异有统计学意义(P<0.05);观察组上腹痛、腹胀、早饱、嗳气、恶心、呕吐等证候积分均优于对照组(P均<0.05);观察组不良反应发生率为8.8%,对照组不良反应发生率为20.8%,观察组不良反应发生率低于对照组(P<0.05)。结论:中西医结合治疗功能性消化不良临床疗效显著,副作用少。

Objective ：To observe the clinical effect of the therapy cff integrative Chinese and western medicine on functional dys- pepsia （FD）. Methods： 135 cases with FD were randomized into control group （67 cases） and observation group （68 cases）. Control group were given Cisapride and Omeprazole Enteric-coated Capsules. Treatment group were additionally given self-formu- lated Stomach-Harmonizing and Distention-Dispersing Decoction. Resuhs：The effective rate was 73. 1% in control group and 91.2% in observation group. By comparison, the difference was statistically significant （P 〈 0.05 ）. The symptom scores of upper abdominal pain, abdominal distention, early satiety, behching, nausea, and vomiting in observation group were better than these in control group （P 〈0.05）. The occurrence rate of adverse reaction in observation group （8.8%） was lower than that in control group （20.8%） （ P 〈 0.05 ）. Conclusion： The therapy of integrative Chinese and western medicine has remarkable effect on FD with little side effects.