肝细胞癌患者射频消融术后的远期疗效评价

Effectiveness Evaluation of Hepatocellular Carcinoma after Radiofrequency Ablation

射频消融已广泛应用于肝细胞癌的治疗,通过文献复习,对肝癌射频消融的远期疗效和影响因素进行总结。≤2 cm的极早期小肝细胞癌,射频消融可以与外科切除术一样作为首选治疗方式,且可以单独应用;非极早期小肝细胞癌,外科切除显示了更高的5年生存率;一些合并明显肝硬化、肝功能较差而不能耐受外科切除术的患者,射频消融为临床医生提供了更好的选择;大肝癌的治疗,射频消融不宜单独应用,联合肝动脉化疗栓塞或经皮无水酒精注射可显著提高远期疗效。影响射频消融疗效的因素有很多,充分了解和认识这些影响因素对于提高肝细胞癌的治疗效果具有重要意义。

Among numerous malignant tumors, the incidence and mortality of hepatocellular carcinoma （HCC） are high, and as a kind of radical treatment, radiofrequency ablation （RFA） has been widely used in the treatment of HCC. It is necessary to sum up reports in recent years and to conclude the major influence factors of long-term curative effect of RFA treatment in order to help physicians make better clinical decisions and to improve survival rates of patients with HCC.