应用BED-CEIA方法估算临沧市2011年HIV-1新近感染率

Estimation of infection rate of HIV- 1 in different populations in Lincang city in 2011with BED-CEIA assay

目的用BED-CEIA方法检测临沧市不同来源艾滋病监测样本中HIV-1新近感染,估算2011年的新近感染率。方法采用连续横断面调查方法,对2011年艾滋病不同来源监测样本中经过血清学检测确认为HIV-1抗体阳性的样本进行BED-CEIA检测,估算HIV-1新近感染率。结果采用BED-CEIA方法检测样本996份,发现HIV-1新近感染110例,感染率为0.27%,新近感染率为0.07(95%CI:0.04%-0.10%)。其中以自愿咨询检测者新近感染率最高,达到2.44%,其次为性病门诊就诊者和强制/劳教戒毒及其他羁押人员体检达到0.43%和0.21%。值得注意的是孕产期人群新近感染率也较高,达到0.13%。结论艾滋病自愿咨询检测者、性病门诊就诊者、感染者配偶及性伴为临沧市HIV新近感染较高人群,孕产妇新近感染率也不容忽视。

Objective To estimate the incidence of HIV- 1 infection among different populations in Lincang city. In2011.by BED- CEIA assay. Methods The samples positive for HIV- 1 ascertained serologically during monitoring werecollected by continuous cross- sectional survey and the incidence of HIV- 1 infection among different populations wereestimated by BED-CEIA assay. Results The 996 positive samples were tested with BED-CEIA assay and 110 samples wereidentified as recent infections with the infection rate of 0.27%, and incidence of 0.07（95% CI： 0.04 0.10%）. The incidence ofvoluntary counseling testing consultants was 2.44%, being the highest, followed by STD clinic patients, those under compulsoryaddiction treatment and addiction treatment through labor as well as other detainees detected through health checkup was0.43% and 0.21%. It was worthy noting that the incidence of pregnant women and gravidae was also high（0.13%）. Conclusion The incidence rate of HIV-1 infection among AIDS voluntary counseling testing consultants, STD clinic patients, spouses andsexual partners of HIV-1 carriers in Lincang city was higher, and attention should also be paid to the status of HIV-1 infectionamong pregnant women and gravidae.