摘要
目的 :对复方黄芩片的溶出度进行了考察 ,为控制药品质量提供依据。方法 :以水为溶出介质 ,按转蓝法操作 ;用HPLC法检测 ,计算复方黄芩片的累积溶出度 ,提取参数 (T50 、Td、m)并对参数进行相关性检验。结果 :不同批次的复方黄芩片溶出参数有极显著性差异 (P <0 .0 1)。结论
Objective: The dissolution of Fufang Huangqin Tablets were determined in order to provide the basis for appraisal of quality of medicine. Methods: According to Chinese pharmacopoeia (2000) dissolution method I and using water. HPLC was adopted for the determination. The accumulative dissolution of Fufang Huangqin Tablets was calculated. The parameters (T 50 、T d、m) obtained from these samples were processed for correlation test. Results: The dissolution of Fufang Huangqin Tablets was remarkably different among batchs ( P < 0.01 ). Conclusion: Inspection of dissolution of Fufang Huangqin Tablets must be attended.
出处
《中成药》
CAS
CSCD
北大核心
2002年第7期500-502,共3页
Chinese Traditional Patent Medicine
