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严格血糖控制对2型糖尿病眼屈光的影响 被引量:3

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摘要 目的观察2型糖尿病患者严格控制血糖3个月内屈光改变,比较初发糖尿病患者和非初发糖尿病患者的差异,并同时观察眼部屈光相关生物测量指标变化以及屈光变化的相关分析。方法对空腹血糖>11.1mmol/L或随机血糖>13 mmol/L的34例2型糖尿病患者进行强化治疗,强化治疗前、治疗后血糖达标和3个月进行眼科常规检查及眼部生物指标测量:眼A超、角膜中央厚度、自动验光仪验光。结果血糖下降达标时,屈光趋向远视改变,第3个月远视趋向减少(左右眼比较P=0.000)。血糖达标时初发糖尿病患者较非初发患者屈光漂移幅度大,初发患者左右眼分别漂移+1.15D、+1.04D,非初发患者左右眼分别为+0.33D、+0.22D,差异有统计学意义(右眼P=0.03,左眼P=0.017),第3个月屈光基本恢复到初始水平(左右眼P>0.05)。屈光改变与基线糖化血红蛋白(Hb A1C)呈正相关,右眼Spearman相关系数r=0.412(P=0.029),左眼r=0.439(P=0.02)。强化治疗3个月内中央角膜厚度、前房深度、晶体厚度、眼轴均无明显变化。结论 2型糖尿病患者血糖下降达标时,屈光趋向远视改变,第3个月远视回退。初发患者的远视漂移较非初发患者幅度大。远视漂移与基线Hb A1C呈正相关,与眼部生物测量指标无关。
出处 《广东医学》 CAS 北大核心 2015年第7期1080-1083,共4页 Guangdong Medical Journal
基金 广东省佛山市医学类科技攻关项目(编号:201308096)
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参考文献9

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二级参考文献7

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