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心肌型脂肪酸结合蛋白在诊断急性冠脉综合征中的应用 被引量：6

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摘要 急性冠脉综合征（acute coronary syndrome,ACS）特指冠心病中急性发病的临床类型,包括不稳定型心绞痛、非ST段抬高心肌梗死以及ST段抬高心肌梗死。其发病的病理生理基础为不稳定的粥样硬化斑块,斑块破裂诱发急性血栓形成,从而引发后续的一系列级联反应,随之发生的心力衰竭、心脏破裂或恶性心律失常,则是临床上ACS患者发病迅速、病死率高的重要原因,因此迅速确诊以便早期治疗,尽早挽救濒临坏死的心肌可极大地改善ACS患者的预后，降低病死率。
作者 刘亚巍 衣志勇 蒋知新 洛佳坤 卢楠
机构地区 中国人民解放军总参谋部警卫局卫生保健处 中国人民解放军第三〇五医院检验科
出处 《广东医学》 CAS 北大核心 2015年第7期1139-1141,共3页 Guangdong Medical Journal
基金 全军"十一五"医药卫生科研基金课题(编号:06MA367)
关键词 急性冠脉综合征 脂肪酸结合蛋白 心肌型 FABP 心脏破裂 恶性心律失常 不稳定型心绞痛 级联反应 斑块破裂 肌钙蛋白
分类号 R542.22 [医药卫生—心血管疾病]
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参考文献26

  • 1THYGESEN K, ALPERT J S, WHITE H D, et al. Joint ESC/ ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction. Universal definition of myocardial infarction [ J ]. Cir- culation, 2007, 116 (22) : 2634 - 2653.
  • 2KARMEN A, WROBLEWSKI F, LADUE J S. Transaminase activi- ty in human blood[ J]. J Clin Invest, 1955, 34(1) : 126 -131.
  • 3GLATZ J F, VAN DER VUSSE G J. Cellular fatty acid - binding protein: their function and physiological significance [ J ]. Prog Lipid Res, 1996, 35(3): 243-282.
  • 4STORCH J, THUMSER A E. The fatty acid transport function of fatty acid - binding protein [ J ]. Biocbim Biopbys Aeta, 2000, 1486(1) : 28 -44.
  • 5ZSCHIESCHE W, KLEINE A H, SPITZER E, et al. Histochemi- cal localization of heart - type fatty - acid binding protein in hu- man and murine tissues [ J ]. Histochem Cell Biol, 1995, 103 (2) : 147 -156.
  • 6MAATMAN R G, VAN DE WESTERLO E M, VAN KUPPEVELT T H, et al. Molecular identification of the liver - and the heart - type fatty acid - binding protein in human and rat kidney. Use of the revers transcrlptase polymerase chain reaction [ J]. Biochem J, 1992, 288(Pt 1) : 285 -290.
  • 7PELSERS M M, HANHOFF T, Van der VOORT D, et al. Brain - and heart - type fatty acid - binding proteins in the brain: tissue distribution and clinical utility [ J ]. Clin Chen, 2004, 50 ( 9 ) : 1568 - 1575.
  • 8BATHIA D P, CARLESS D R, VISWANATHAN K, et al. Serum 99th centile values for two heart - type fatty acid binding protein assays[ J]. Ann Clin Biochem, 2009, 46(Pt 6) : 464 -467.
  • 9NIIZEKI T, TAKEISHI Y, TAKABATAKE N, et al. Circulating levels of heart - type fatty acid - binding protein in a general Japa- nese population : effects of age, gender, and physiologic characte- ristics[J]. Circ J, 2007, 71(9) : 1452 -1457.
  • 10PELSERS M M, CHAPELLE J P, KNAPEN M, et al. Influence of age and sex and day - to - day and within - day biological variation on plasma concentrations of fatty acid - binding protein and myoglobin in healthy subjects[J]. Clin Chem, 1999, 45(3) : 441 -443.

二级参考文献17

  • 1Orak M,Ustundag M,Guloglu C,et al. The role of the hearttype fatty acid binding protein in the early diagnosis of acute coronary syndrome and its comparison with troponin I and creatine kinase-MB isoform. Am J Emerg Meal,2010,28=891- 896.
  • 2Dekker MS,Mosterd A,van't Hof AW,et al. Novel biochemical markers in suspected acute coronary syndrome:systematic review and critical appraisal. Heart,2010,96: 1001-1010.
  • 3Kim Y, Kim H, Kim SY, et al. Automated heart-type fatty acid-binding protein assay for the early diagnosis of acute myocardial infarction. Am J Clin Pathol, 2010,134 : 157-162.
  • 4McCann CJ ,Glover BM, Menown BA,et al. Investigation of a multimaker approach to the initial assessment of patients with acute chest pain. Adv Ther,2009,26:531-534.
  • 5de Lemos JA, Morrow DA, Bentley J H, et al. The prognostic value of B-type natriuretic peptide in patients with acute eoronary syndromes. N Eng J Med,2001,345:1014-1021.
  • 6Valente S, Lazzeri C, Chiostri M, et al. NT-proBNP on admission for early risk stratification in STEMI patients submitted to PCI. Relation with extension of STEMI and inflammatory markers. Int J Cardiol, 2009,132 : 84-89.
  • 7Mad P,Dornanovits H, Fazelnia C, et al. Human heart-type fatty acid-binding protein as a point of-care test in the early diagnosis of acute myocardial infarction. QJ Med,2007,100: 201- 210.
  • 8Figiel L, Kasprzak JD, Peruga J, et al. Heart-type fatty acid binding protein--a reliable marker of myocardial necrosis in a heterogeneous group of patients with acute coronary syndrome without persistent ST elevation. Kardiol Pol, 2008,66: 253-261.
  • 9Viswanathan K, Kilcullen N, Morrell C, et al. Heart-type fatty acid-binding protein predicts long-term mortality and re-infarction in consecutive patients with suspected acute coronary syndrome who are troponin negative. J Am Coil Cardiol, 2010,55 : 2590-2598.
  • 10O' Donoghue M, de Lemos JA, Morrow DA, et al. Prognostic utility of heart-type fatty acid-binding protein in patients with acute coronary syndromes. Circulation, 2006,114 : 550-557.

共引文献31

同被引文献55

  • 1杨溶海,方长庚,梁建光.丹参多酚酸盐对冠心病心力衰竭患者左心功能及血清心型脂肪酸结合蛋白的影响[J].中国老年学杂志,2014,34(9):2322-2324. 被引量：37
  • 2脑卒中患者临床神经功能缺损程度评分标准（1995）[J].中华神经科杂志,1996,29(6):381-383. 被引量：15727
  • 3陈灏珠,林果为.实用内科学[M].13版.北京:人民卫生出版社,2009:919.
  • 4KOYLU R, CANDER B, DUNDAR Z D, et al. The importance of I4 - FABP in determining the severity of carbon monoxide poiso- ning[J]. J Clin Med Res, 2011, 3(6) : 296 -302.
  • 5ERENLER A K, YARDAN T, BAYDIN A, et al. Heart -type fat- ty acid - binding protein as a potential biomarker of acute carbon monoxide poisoning[J]. Am J Emerg Med, 2013, 31(8) : 1165 - 1169.
  • 6Skagen K,Skjelland M,Russell D,et al.Large-vessel occlusion stroke effect of recanalization on outcome depends on the national institutes o health stroke scale score[J].J Stroke Cerebrovasc Dis,2015;24(7)1532-9.
  • 7Takagi T,Kato T,Sakai H,et al.Early neurologic improvement based on the national institutes of health stroke scale score predicts favorable outcome within 30 minutes after undergoing intravenous recombinant tissue plasminogen activator therapy[J].J Stroke Cerebrovasc Dis,2014;23(1):69-74.
  • 8Vosbergen S , Janzen J , Stoppers PJ, et al. A qualitative participatory study to identify experiences of coronary heart disease patients to support the development of online self- management services[J]. Int J Med Inform, 2013, 82 (12) : 1183-1194.
  • 9Girinsky T, M'Kacher R, Lessard N, et al. Prospective coro- nary heart disease screening in asymptomatic Hodgkin lym- phoma patients using coronary computed tomography angiog- raphy: Results and risk factor analysis[J]. Int J Radlat Oncol Biol Phys, 2014, 89(1):59-66.
  • 10Xia J, Yi L, Liu N, et al. Human Plasma Metabolic Profiles of Coronary Heart Disease by Gas Chromatography-Mass Spectrometry with Monte Carlo Tree Approach [J]. Analytical Letters, 2012, 45(13/15) ~ 2185-2197.

二级引证文献53

广东医学
2015年 第7期

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