摘要
目的:分析1990年与2010年中国15岁以上人群慢性阻塞性肺疾病(COPD)的疾病负担变化情况。方法利用2010年全球疾病负担研究结果,分析1990年和2010年中国15岁以上人群COPD的死亡、患病情况,及其过早死亡损失寿命年(YLL)、伤残损失寿命年(YLD)及伤残调整寿命年(DALY),比较中国1990年和2010年COPD导致的DALY、标化死亡率和DALY率的变化情况。结果2010年我国15岁以上居民因COPD死亡的人数为93.4万例(男性53.4万例,女性40.0万例),比1990年(142.5万例,男性70.5万例,女性72.0万例)减少34.5%(男性减少24.3%,女性减少44.4%);2010年COPD的患病人数为4176.4万例(男性2211.1万例,女性1965.3万例),比1990年(2938.2万例,男性1559.9万例,女性1378.3万例)增加了42.1%(男性增加41.7%,女性增加42.6%)。我国15岁以上居民COPD的标化死亡率由1990年的235.2/10万下降为2010年的90.5/10万,下降幅度达61.5%。我国1990年和2010年15岁以上居民COPD标化患病率分别为4.2%和3.9%。2010年我国因COPD造成的DALY、YLL和YLD分别为1659.8万、1294.6万及365.2万人年。与1990年(256.7万人年)相比,2010年我国因COPD造成的YLD上升了42.3%。标化YLL率由1990年的3756.9/10万下降为2010年的1235.6/10万,标化DALY率由1990年的4120.1/10万下降为2010年的1575.9/10万,标化YLD率由1990年的363.2/10万下降为2010年的340.3/10万。结论与1990年相比,虽然2010年COPD所致的DALY有了明显下降,但因伤残导致的疾病负担有所上升。
Objective To analyze the disease burden of chronic obstructive pulmonary disease (COPD) among people aged over 15 years in 1990 and 2010 in China. Methods The estimation of China data for the Global Burden of Disease Study 2010 (GBD 2010) was used to analyze the mortality and prevalence as well as the years of life lost due to premature mortality(YLL), years lived with disability(YLD) and disability-adjusted life years (DALY) of COPD in China in 1990 and 2010 for Chinese people aged 15 years and above. The death rate and DALY rate of COPD in China in 1990 and 2010 were compared. Results In 2010, 0.934 million people (0.534 million men and 0.400 million women) aged over 15 years died from COPD, decreased 34.5% (24.3% for men and 44.4% for women) compared with that in 1990 (1.425 million with 0.705 million men and 0.720 million women). There were 41.764 million COPD patients in 2010 (22.111 million men and 19.653 million women), increased 42.1%(41.7%for men and 42.6%for women) compared with 1990 (29.382 million patients with 15.599 million men and 13.783 million women). The mortality rate of COPD decreased for 61.5%from 2.352/100 000 in 1990 to 90.5/100 000 in 2010. The prevalence rate of COPD was 4.2%and 3.9%in 1990 and 2010,respectively. The DALY, YLL and YLD due to COPD was 16.598, 12.946, and 3.652 million person years,respectively in 2010. The YLD increased 42.3%compared with 1990 (2.567 million person years). From 1990 to 2010, the age-standardized DALY rate, YLL rate and YLD rate decreased from 4 120.1/100 000 to 1 575.9/100 000, from 3 756.9/100 000 to 1 235.6/100 000 and from 363.2/100 000 to 340.3/100 000,respectively. Conclusion Although there was significant decrease of DALY due to COPD in 2010, compared to 1990, the YLD burden is still increasing.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2015年第4期334-338,共5页
Chinese Journal of Preventive Medicine
基金
国家科技支撑计划(2013BAI04B02)
人社部2013年留学人员科技择优项目
关键词
肺疾病
慢性阻塞性
生命统计
患病代价
Pulmonary disease,chronic obstructive
Vital statistics
Cost of illness