广东常用中药材及饮片二氧化硫残留量研究

Sulfur Dioxide Residues Research of Traditional Chinese Medicine in Guangdong

目的对广东省常用的30种中药材及饮片中二氧化硫残留情况及贮藏时间残留规律进行检测分析,为安全用药提供参考。方法采用《中国药典》2010年版第一增补本附录ⅨU方法检测二氧化硫残留。结果在检测的150批次中药材及饮片样品中,56批次有二氧化硫残留量超标,占药材总批次的37.3%;不同品种药材二氧化硫残留量差别比较大,有的高达1 000 mg/kg,同品种不同批次药材之间二氧化硫残留量差异也比较大。晾晒、烘干、贮藏时间延长后的中药材二氧化硫含量减少。结论部分中药材二氧化硫残留量过高,中药应用硫黄熏蒸迫切需要有效的管理与监督。晾晒、烘干、延长贮藏时间能使中药材及饮片二氧化硫含量减少。

OBJECTIVE To detect and analyze the situation of sulfur dioxide residues in herbal medicine and the rule of the sulfur dioxide residue amount with the storage duration in Guangdong,so as to provide a reference for its safe medication. METHODS The method in Appendix Ⅸ U,Enlarged Edition Ⅰ,＂Chinese Pharmacopoeia ＂ 2010 was used to detect the sulfur dioxide.RESULTS In the 150 batches of Chinese herbal medicine samples tested,contents of sulfur dioxide in 56 batches of Chinese herbal medicines exceed the standard,accounting for 37. 3% of the total batches of medicinal materials; differences among the amounts of sulfur dioxide in different herbs were relatively large with some more than 1 000 mg / kg,while the differences among the amounts of sulfur dioxide in different batches of the same herb were also large. The sulfur dioxide residues had reduced in sun-cured,dried or prolonged-time stored herbs. CONCLUSION Some Chinese herbal medicines have excessive sulfur dioxide residues,and the application of sulfur fumigation of Chinese herbal medicine urgently needs effective management and supervision. Sun-curing,drying and prolonged-time storage can reduce the sulfur dioxide content of Chinese herbal medicines.