人工真皮移植二期手术疗法对肛周化脓性汗腺炎的治疗分析

Treatment analysis of two-stage skin grafting with artificial dermis for perianal hidradenitis suppurativa

目的：探讨人工真皮移植二期手术对肛周化脓性汗腺炎的治疗效果。方法选择肛周化脓性汗腺炎患者20例。在一期手术中，切除所有病变的皮肤以及表浅皮下脂肪组织，健康深层皮下脂肪组织予以保留。然后将人工真皮移植到保留的深层皮下组织上。2周后行二期手术，将中厚皮片移植到缺损皮肤。对患者移植物的成活、疾病复发以及术后9~28个月的随访表现进行评估。结果19例患者病灶处的皮肤移植成功，仅有1例患者化脓性汗腺炎复发，这例患者再次手术后，外观恢复良好。结论人工真皮移植二期手术疗法对肛周化脓性汗腺炎具有较好的临床效果。

Objective To investigate the effect of two-tage skin grafting with artificial dermis for perianal hidradenitis suppurativa. Methods A total of 20 cases diagnosed as perianal hidradenitis suppu-rativa in our hospital were selected from 2011 to 2013. In the first-stage operation,all diseased skin inclu-ding the superficial subcutaneous fatty tissue was excised,and normal deep subcutaneous fatty tissue was preserved. Then,artificial dermis was grafted to the preserved fatty tissue. After two weeks,split-hickness skin grafts were used for the skin defects as the second-tage operation. Graft success,recurrence and post-operative appearance were evaluated in these patients who were followed up for 9 to 28 months. Results Skin grafts of all 19 patients were successfully survived. The recurrence of hidradenitis suppurativa oc-curred in only one patient. This patient was treated with reoperation and the postoperative appearance was welly recovered. Conclusion Two-tage skin grafting with artificial dermis appears to be a good treatment option for perianal hidradenitis suppurativa.