不同类型早泄射精潜伏期与慢性前列腺炎症状评分的相关性调查

Relationships between intravaginal ejaculatory latency time and national institutes of health-chronic prostatitis symptom index in the four types of premature ejaculation

目的探讨不同类型早泄射精潜伏期（IELT）与美国国立卫生研究院前列腺炎症状评分（NIH-CPSI）的相关性。方法对2013年2月至2014年5月因早泄而就诊于安徽医科大学第一附属医院男科门诊的485名早泄患者和372名健康体检者（来自体检中心，自述无早泄）进行相关检查和问卷调查。调查的内容包括基本人口信息学特征、IELT和NIH-CPSI等。结果早泄组的IELT显著低于自述无早泄组（简称无早泄组），而早泄组的NIH-CPSI评分显著高于无早泄组。在不同类型早泄组中，获得性早泄（APE）的NIH-CPSI的总分及各分项得分值最高，早泄样射精功能障碍（PLED）的IELT最长。早泄患者的IELT与NIH-CPSI评分呈负相关性，其中APE组的IELT与NIH-CPSI总分及各分项得分的相关性最强：IELT与NIH．CPSI总分、疼痛症状评分、排尿症状评分、生活质量评分的相关系数分别为-0．67、-0．71、-0．69、-0．63（P均〈0．001）。结论早泄患者的NIH-CPSI评分显著高于无早泄组，早泄患者的IELT与NIH-CPSI评分呈负相关性，APE组的IELT与NIH-CPSI总分及各分项得分的负相关性最强。

Objective To analyze the relationships between intravaginal ejaculatory latency time （IELT） and national institutes of health-chronic prostatitis symptom index （NIH-CPSI） in the four types of premature ejaculation （PE）; Methods From February 2013 to May 2014, a cross-section survey was carried out in 485 patients with PE and an cohort of 372 age- matched healthy men who were fromthe andrology outpatient clinic and health examination center, respectively. Subjects were required to complete a questionnaire, including demographic information, medical and sexual history （e.g., IELT）, and self-estimated scales （e.g., NIH-CPSI）. Results Patients with PE had worse NIH-CPSI scores and lower IELT as compared with that of healthy men without PE （P〈0.001 for all）. Moreover, total and subdomain scores of NIH-CPSI were higher in men with APE, and IELT was higher in men with PLED. IELT was negatively associated with NIH-CPSI scores in men with complaints of PE. Negative relationships between total and subdomain scores of NIH-CPSI and IELT were stronger in men with APE （total scores： adjusted r = -0.67, P〈0.001; pain symptoms： adjusted r = -0.71, P〈0.001; urinary symptoms： adjusted r = -0.69, P〈0.001; quality of life impact： adjusted r = -0.63, P 〈 0.001）. Conclusion Men with complaints of PE had worse NIH-CPSI scores compared with men without complaints of PE. IELT was negatively associated with NIH-CPSI scores in men with complaints of PE. Relationships between IELT and NIH-CPSI scores were strongest in men with APE.