824例婴幼儿血清25-羟基维生素D检测结果分析

Analysis on detection results of serum 25-hydroxy vitamin D in 824 infants

目的：了解广州市区0~6岁婴幼儿的维生素D营养状况。方法：收集在广东省妇幼保健院儿保科门诊进行常规保健的824例0~6岁婴幼儿血清,采用酶联免疫吸附试验（ELISA）检测血清25-羟基维生素D[25-（OH）D]。结果：824例0~6岁婴幼血清25-（OH）D的平均水平为（69.52±57.09）nmol/L,其中充足组213例占25.85%,有73.66%的婴幼儿25-（OH）D处于较低水平（51.33%不足、19.42%缺乏、2.91%严重缺乏）。0~6岁婴幼儿血清25-（OH）D水平在不同性别间差异无统计学意义（P〉0.05）;3~6岁组婴幼儿血清25-（OH）D水平明显低于〈1岁组,差异有统计学意义（P〈0.05）。结论：广州市区0~6岁婴幼儿血清25-（OH）D水平普遍偏低,应重视婴幼儿血清25-（OH）D的检测。

Objective： To understand the nutritional status of vitamin D among 0-6-year-old infants in Guangzhou. Methods： Serum samples of 824 healthy infants receiving conventional health care in Outpatient of Pediatric Health Care in the hospital were collected, ELISA was used to detect serum 25-hydroxy vitamin D levels. Results： The average value of serum 25-hydroxy vitamin D was （69. 52± 57.09） nmol/L, only 213 infants （25.85%） had enough 25-hydroxy vitamin D, the levels of 25-hydroxy vitamin D in 73. 66% of the in- fants were relatively low （ not enough in 51.33% of the infants, deficiency in 19.42% of the infants, and severe deficiency in 2.91% of the infants） . There was no statistically significant difference in serum 25-hydroxy vitamin D level between boys and girls （P〉0. 05 ） ; serum 25-hydroxy vitamin D level in 3-6＇year-old infant group was statistically significantly lower than that in infants under one year （P〈 0. 05 ） . Conclusion ： Serum 25-hydroxy vitamin I3 levels in 0-6-year-old infants are generally low, serum 25-hydroxy vitamin D detec- tion among infants should be paid more attention to.