期刊文献+

老年骨折后急性脑梗死患者C-反应蛋白、纤维蛋白原水平及意义 被引量:2

下载PDF
导出
摘要 目的动态观察老年骨折患者急性脑梗死的发生与C-反应蛋白(CRP)、纤维蛋白原(FBI)水平的相关性。方法 140例神经内科住院脑梗死患者,分为老年骨折后脑梗死组(70例)与非骨折脑梗死组(70例),入院后第2天采集血液,化验C-反应蛋白、纤维蛋白原,对两组上述两项指标进行统计学分析。结果老年骨折后急性脑梗死组C-反应蛋白、纤维蛋白原含量均明显高于非骨折脑梗死组,差异具有统计学意义(P<0.05)。结论 CRP、FBI参与脑梗塞的病理过程,骨折后上述两项指标升高,是老年骨折患者患急性脑梗死的危险因素。检测CRP、FIB可评病情及预后,同时骨科医生可通过检测二者,预防骨折后脑梗死的发生。
出处 《中国实用医药》 2015年第12期67-68,共2页 China Practical Medicine
  • 相关文献

参考文献9

  • 1Ridker PM, Silvertown JD. Inflamation, C-reactive protein, and atherothrombosis. J Periodontol, 2008, 79(8 Suppl): 1544.
  • 2Cao J J, Thach C, Manolio TA, et al. C-reactive protein, carotid intima-mediat thickness, and incidence of ischemic stroke in the elderly: the Cardiovascular Health Study. Circulation, 2003, 108(2): 166-170.
  • 3王天舒,滕军放.急性脑梗死患者血清铁蛋白与超敏C反应蛋白检测[J].郑州大学学报(医学版),2010,45(4):657-658. 被引量:10
  • 4Meade TW, North WR, Chakrabarti R, et al. Haemostatic function and cardiovacular death: early results of a prospective study. Lancet, 1980, 1(8177):1050-1054.
  • 5Teiada JC, Hernandez E, Chimeno J, et al. Acute pancreatitis mimicking acute inferior myocardial infarction. Anqiology, 2008, 59(3):365-367.
  • 6许艳,高佩琦,马波,梁庆成,赵永波.急性脑梗塞的红细胞膜流动性及生化指标改变[J].哈尔滨医科大学学报,2000,34(1):24-25. 被引量:12
  • 7Ryu JK, Mclarnon JG. VEGF receptor antagonist Cyclo-VEGI reduces inflammatory reactivity and vascular leakiness and is neuroprotective against acute excitotoxic striatal insult. J Neuro inflammation, 2008, 59(5): 18.
  • 8Ryu JK, Mclarnon JG. A leaky blood-brain barriier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer' s disease brain. J Cell Mol Med, 2009, 13(9A):2911-2925.
  • 9周帅,赵洛沙,王浩坤,邱承杰,宗永华,王杨.纤维蛋白原-β148C/T基因多态性与冠心病的关系[J].山东医药,2009,49(41):10-12. 被引量:7

二级参考文献23

  • 1戴宝珠,朱秉武.腔隙性脑梗塞患者血液流变学与血脂变化的观察[J].实用老年医学,1995,9(6):271-272. 被引量:8
  • 2Blake G J, Schmitz C, Lindpaintner K, et al. Mutation in the promoter region of the β-fibrinogen gene and the risk of future myocardial infarction, stroke and venous thrombosis [ J ]. Euro Heart J, 2001,22 (24) :2262-2266.
  • 3Humphries SE, Luong LA, Montgomery HE, et al. Gene-environment interaction in the determination of levels of plasma fibrinogen [ J]. Thromb Haemost, 1999,82(2) :818-825.
  • 4Jaegar BR, Labarrere CA. Fibrinogen and atherothroinbosis:vuinerable plaque or vuinerable patinent[ J]. Herr, 2003, 28(6) :530.
  • 5Behague I, Poirier O, Nieaud V, et al. Beta fibrinogen gene polymorphisms are associated with plasma fibrinogen and coronary artery disease in patients with myocardial infarction [ J ]. Circulation, 1996,93(3) :440-449.
  • 6Schmidt H, Schmidt R, Niederkorn K, et al. Beta-fibrinogen gene polymorphism(C1483T) is associated with carotid atherosclerosis results of the Austrian Stroke Prevention Study [ J ]. Arterioscler Thromb Vasc Biol, 1998, 18(3) :487-492.
  • 7Pongracz E, Andrikovics H, Bernat IS, et al. Connection between genetically determined blood coagulation factors and hemorheology [ J]. Clin Hemorhcol Microcirculation ,2008,39 (1-4) :333-341.
  • 8Danesh J, Collins R, Peto R. Chronic infections and coronary heart disease : is there a link [ J ]. Laneet, 1997, 350 ( 9075 ) : 430-436.
  • 9Yang Q, Toiler GH, Cupples LA, et al. A genome-wide search for genes affecting circulating fibrinogen levels in the Framingham Heart Study[J]. Thromb Res,2003 ,110( 1 ) :57-64.
  • 10Kang JO. Chronic iron overload and toxicity: clinical chemistry perspective[J]. Clin Lab Sci,2001,1d(3 ) :209.

共引文献22

同被引文献22

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部