麻杏二陈汤加味治疗慢性阻塞性肺疾病急性加重期80例临床观察

Clinical Observation of Using Modifying Ma' xing Erchen Decoction to Treat 80Cases of Acute Exacerbation of Chronic Obstructive Pulmonary Diseases

目的:观察麻杏二陈汤加味治疗慢性阻塞性肺疾病(中医病名:肺胀)急性加重期(痰湿蕴肺证)的临床疗效。方法:将80例慢性阻塞性肺疾病急性加重期患者80例随机分入治疗组和对照组,每组40例,两组均予西医常规治疗(抗感染、化痰、平喘、吸氧、对症治疗),治疗组在此基础上加用中药麻杏二陈汤加味口服,两组疗程均为14天。观察两组患者治疗前后在咳嗽、痰量、呼吸困难、肺部啰音、嗜睡、腹胀、纳差、便溏、肺功能、6分钟步行距离等的改善情况。结果:治疗组总有效率为92.5%,对照组总有效率为75%,两组总有效率比较有显著性差异(P<0.05),且治疗组对咳嗽、痰量、肺部啰音、腹胀、便溏、肺功能、6分钟步行距离的改善作用优于对照组(P<0.05)。结论:麻杏二陈汤加味治疗慢性阻塞性肺疾病急性加重期(痰湿蕴肺证)疗效优良,可供临床借鉴。

Objective ： To observe the effect of modifying Maxing Erchen Decoction on treating acute exacerbation of chronic obstructive pulmonary diseases. Methods： 80patients with acute exacerbation of chronic obstructive pulmonary diseases were ran- domly divided into 2groups ： the treatment group and the controlled group with 40cases in each. The two groups were given con- ventional western medicine treatment （anti infective, reduce phlegm, relieving asthma and symptomatic treatment）, the treat- ment group were given oral modifying Maxing Erchen Decoction based on the conventional western medicine treatment, the course of treatment in the two groups was 14days. Observing the effect of the two groups in cough, phlegm, dyspnea, pulmonary rales, lethargy, abdominal distension, anorexia, loose stools, pulmonary function, 6minutes walking distance. Results： The total ef- fective rate was 92. 5% in the treatment group and 75% in the controlled group, there was significant difference between the two groups （P〈0. 05）, and the treatment group was better than the controlled group in improving effect of cough, phlegm, pulmo- nary rales, abdominal distension, loose stools, pulmonary function and 6minutes walking distance. Conclusion： Treating acute exacerbation of chronic obstructive pulmonary diseases in way of modifying Maxing Erchen Decoction has a good curative effect for clinical reference.